冠状动脉CTA联合CT心肌灌注成像诊断冠心病:Meta分析

发布时间：2018-02-26 22:32

本文关键词： 冠状动脉疾病体层摄影术 X线计算机血管造影术灌注成像 Meta分析　出处：《中国医学影像技术》2017年09期 　论文类型：期刊论文

【摘要】：目的采用Meta分析评估冠状动脉CT血管成像(CCTA)联合心肌CT灌注成像(CTP)诊断冠心病的价值。方法检索PubMed、Wed of Science、Cochrane Library、中文学术期刊数据库(CNKI)及万方数据库自建库以来至2016年12月、国内外公开发表的、关于CCTA联合心肌CTP诊断冠心病的中英文文献。按照诊断试验标准筛选文献,采用诊断准确性研究的质量评价工具-2(QADAS-2)评分标准进行质量评价,采用Meta-disc 1.4软件分析合并效应量并绘制汇总受试者工作特征(SROC)曲线,计算曲线下面积(AUC)。结果共纳入5篇文献,共611支冠状动脉,在血管水平CCTA联合CTP合并敏感度、特异度、诊断比值比、阳性似然比、阴性似然比及各自的95%可信区间分别为0.96(0.92,0.98)、0.91(0.88,0.94)、206.14(100,424.94)、9.33(5.57,15.61)、0.06(0.03,0.13);SROC曲线的AUC为0.977。结论冠状动脉CTA联合心肌CTP对冠心病具有较高的诊断价值。
[Abstract]:Objective to evaluate the diagnostic value of coronary artery CT angiography (Meta) combined with myocardial CT perfusion imaging (CTP) in the diagnosis of coronary artery disease (CHD) by Meta. Methods We searched PubMeded of Science of Science Cochrane Library (CNKI) and Wanfang database from December 2016 to December 2016. The Chinese and English literature on the diagnosis of coronary heart disease with CCTA combined with myocardial CTP was published at home and abroad. According to the diagnostic test criteria, the literature was screened, and the quality evaluation was carried out by using the quality evaluation tool of diagnostic accuracy study-2QADAS-2. Meta-disc 1.4 software was used to analyze the combined effect and draw the operating characteristics of the subjects. The area under the curve was calculated. Results A total of 611 coronary arteries were included, and the sensitivity and specificity of CCTA combined with CTP at vascular level were obtained. The diagnostic ratio, the positive likelihood ratio, the negative likelihood ratio and their respective 95% confidence intervals were 0.96 ~ 0.92n 0.98 ~ 0.98 ~ 0.98 ~ 0.94 ~ 0.94 ~ 0.69 ~ (9.33) ~ (5.57) ~ (15.61) ~ 0.030.13SROC (AUC = 0.977) respectively. Conclusion Coronary artery CTA combined with myocardial CTP has a higher diagnostic value for coronary heart disease than that for coronary artery disease (P < 0.05, P < 0.05, P < 0.05), and the ratio of positive likelihood to likelihood, negative likelihood ratio and their respective 95% confidence intervals are 0.96 ~ 77.Conclusion Coronary artery CTA combined with myocardial CTP is valuable in the diagnosis of coronary heart disease.
【作者单位】：暨南大学附属第一医院医学影像中心;
【分类号】：R541.4;R816.2

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