急性脑梗死全脑CT灌注成像扫描时间优化

发布时间：2018-03-11 01:24

本文选题：脑梗死　切入点：体层摄影术　出处：《中国医学影像技术》2017年10期 　论文类型：期刊论文

【摘要】：目的探讨缩短扫描时间对急性脑梗死全脑CT灌注(CTP)图像质量和灌注参数值的影响。方法回顾性分析30例诊断为单侧急性脑梗死患者的全脑CTP资料。按不同扫描时间(56s、52s、48s、44s、40s及36s)分组,对灌注数据进行图像后处理,获得各组上矢状窦灌注时间密度曲线(TDC)、灌注伪彩图和灌注参数值,并记录上矢状窦首次通过时间。结果与扫描时间56s组比较,52s组及48s组CTP图像质量差异无统计学意义(P均0.05)。扫描时间52s组、48s组、44s组、40s组和36s组CTP图像质量主观评分与上矢状窦首次通过时间呈负相关。与扫描时间56s组比较,当扫描时间缩短至44s及以下时,对部分灌注参数值的测量差异有统计学意义(P均0.05)。结论适当缩短全脑CTP扫描时间,在保证CTP图像质量和灌注值测量准确性同时,可减少辐射剂量,推荐全脑CTP选择延迟8s,扫描时间48s。
[Abstract]:Objective to investigate the effect of shortening scanning time on the image quality and perfusion parameters of acute cerebral infarction with global CT perfusion. Methods the CTP data of 30 patients with unilateral acute cerebral infarction were retrospectively analyzed. After processing the perfusion data, the perfusion time density curve of the upper sagittal sinus was obtained, and the perfusion pseudochromogram and perfusion parameters were obtained. The first transit time of superior sagittal sinus was recorded. Results there was no significant difference in the CTP image quality between 52s group and 48s group compared with the scan time 56s group (P < 0.05). The subjective score of CTP image quality of the 52s group, 48s group (44s group) and 36s group (36s group) was not significantly different from that of the 52s group (52s group) and the 48s group (48s group). There was a negative correlation between the first transit time of superior sagittal sinus and the scanning time of 56 s group. When the scanning time was shortened to 44 s and less than 44 s, there were significant differences in the measurement of some perfusion parameters (P < 0.05). Conclusion shortening the scanning time of whole brain CTP can ensure the quality of CTP images and the accuracy of perfusion measurement at the same time. It is recommended that the whole brain CTP should be delayed for 8 s and scan time for 48 s.
【作者单位】：中国医科大学附属第四医院放射科;
【基金】：辽宁省自然科学基金(2013021035)
【分类号】：R743.3;R816.1

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