双源CT冠状动脉成像联合腺苷负荷CT心肌灌注在诊断冠心病心肌缺血中的应用分析

发布时间：2018-03-11 11:29

本文选题：冠心病　切入点：冠状动脉狭窄　出处：《中华老年心脑血管病杂志》2016年10期 　论文类型：期刊论文

【摘要】：目的探讨双源CT冠状动脉定量分析联合腺苷负荷CT心肌灌注(CTP)扫描在诊断冠心病心肌缺血中的应用分析。方法选择冠状动脉狭窄50%的冠心病患者68例(共计126支病变血管),行双源CT冠状动脉成像及腺苷负荷CTP,按照是否出现CTP异常分为CTP-组(70支)及CTP+组(56支),分析2组各个病变分支在最小管腔面积狭窄度、最小管腔直径狭窄度、斑块负荷、斑块体积、斑块最大厚度、病变长度、斑块性质及钙化积分方面的差异。结果 CTP-组与CTP+组脂质斑块体积和纤维-脂质斑块体积比较,差异无统计学意义(P0.05)。CTP+组最小管腔面积狭窄度、最小管腔直径狭窄度、斑块负荷、斑块体积、斑块最大厚度、病变长度及钙化积分明显高于CTP-组,差异有统计学意义[(69.3±15.2)%vs(59.5±9.2)%,(63.3±10.5)%vs(55.8±5.5)%,(69.9±8.2)%vs(57.5±6.5)%,67.3mm3 vs 43.2mm3,11.5mmvs 6.2mm,2.5mmvs 2.0mm,(281.1±242.4)分vs(107.2±63.8)分,P0.05,P0.01)]。结论双源CT冠状动脉成像联合腺苷负荷CTP不仅可以对冠状动脉进行解剖学分析,同样也可以对其进行功能学分析。
[Abstract]:Objective to investigate the application of dual-source CT coronary artery quantitative analysis combined with adenosine loaded CT myocardial perfusion (CTP) scan in the diagnosis of coronary heart disease myocardial ischemia. Methods 68 patients with coronary artery disease with coronary artery stenosis 50% (total 126 branches) of coronary artery disease were selected. Coronary arteriography and adenosine loading were performed in two groups: CTP- group (70 branches) and CTP group (56 branches). The degree of minimal lumen area stenosis of each lesion branch in two groups was analyzed, and the two groups were divided into two groups: CTP- group (n = 70) and CTP group (n = 56). The differences of minimum lumen diameter stenosis, plaque load, plaque volume, plaque maximum thickness, lesion length, plaque property and calcification score were compared between CTP- group and CTP group. The minimum lumen area stenosis, minimum lumen diameter stenosis, plaque load, plaque volume, plaque maximum thickness, lesion length and calcification score in CTP group were significantly higher than those in CTP- group. The difference was statistically significant [69.3 卤15.2vsl 59.5 卤9.2m 2]. Conclusion Dual-source CT coronary angiography combined with adenosine loading CTP can not only anatomize the coronary artery, but also analyze the function of the coronary artery by dual-source CT coronary angiography combined with adenosine load CTP (67.5 卤8.5mm3 vs 43.2mm 311.5mm vs 6.2mm-1 卤242.4mm).
【作者单位】：河南中医药大学第一附属医院放射科;
【基金】：河南省中医药科学研究专项课题(2015ZY01003)
【分类号】：R541.4;R816.2

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