侵袭性纤维瘤病CT、MRI强化特征及病理基础

发布时间：2018-04-01 13:05

本文选题：纤维瘤　切入点：磁共振成像　出处：《中国医学影像学杂志》2017年09期

【摘要】：目的探讨侵袭性纤维瘤病(AF)的CT、MRI表现,重点分析其强化特征及病理关系,以提高诊断准确性。资料与方法回顾性分析33例经病理证实的AF患者的影像资料,并与术后病理结果进行对照,探讨特征影像的病理基础。结果 33例患者中,腹外型17例,腹壁型4例,腹内型12例;15例呈浸润性生长,18例呈膨胀性生长。CT扫描8例呈均匀渐进性强化;1例病灶周围强化,中心未见明显强化;1例病灶边缘包膜强化;23例病灶呈不均匀、渐进性强化,其中9例增强后稍低密度区明显强化,稍高密度区轻度强化,呈现密度"反转"特征。MRI示7例病灶信号不均,以稍长T1、稍长T2信号为主,其中5例可见不规则短T2信号区,增强后稍长T1、稍长T2信号区强化明显,短T2信号区轻度强化。病理镜下见肿瘤由不同比例的梭形成纤维细胞和胶原纤维组成,细胞密集区域对应稍低密度、长T2信号区,增强后明显强化;而胶原纤维丰富区对应稍高密度、短T2信号区,增强后轻度强化。结论 AF的CT和MRI强化方式具有一定的特征性,有助于术前诊断。
[Abstract]:Objective to investigate the CT MRI findings of invasive fibromatosis (AFD), and to analyze its enhanced features and pathological relationship in order to improve the diagnostic accuracy.Materials and methods the imaging data of 33 patients with AF confirmed by pathology were retrospectively analyzed and compared with the pathological results after operation to explore the pathological basis of characteristic images.Results among the 33 patients, 17 were abdominal external type, 4 were abdominal wall type, 15 were intraabdominal type and 15 were infiltrative growth. Ct scan showed homogeneous progressive enhancement in 1 case.No obvious enhancement was seen in the center of the lesion. In 1 case, the lesions were uneven and progressive in 23 cases. Among them, 9 cases showed slight enhancement in the low density area and slight enhancement in the slightly high density area.MRI showed that the signal intensity was uneven in 7 cases, including slightly longer T _ 1 and slightly longer T _ 2 signals. Among them, 5 cases showed irregular short T _ 2 signal area, slightly longer T _ 1 signal area after enhancement, slight enhancement in short T _ 2 signal area and slight enhancement in short T _ 2 signal area.Pathological examination showed that the tumor was composed of fusiform fibroblasts and collagen fibers of different proportions. The dense area of cells was a little low density, the long T2 signal region was obviously enhanced, while the rich area of collagen fiber was a little higher density, and a short T2 signal region.Mild enhancement after enhancement.Conclusion CT and MRI enhancement of AF are characteristic and helpful for preoperative diagnosis.
【作者单位】：新疆维吾尔自治区人民医院放射影像中心;
【分类号】：R445.2;R730.44

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