小鼠过度运动状态下内分泌症状特征研究分析

发布时间：2018-04-01 14:19

本文选题：小鼠　切入点：过度运动　出处：《科技通报》2015年07期

【摘要】：目的:分析小鼠过度运动状态下内分泌症状特征。方法:将小鼠随机分成空白对照组、常规运动组、过度运动组三组,每组各10只,空白对照组每天无任何特殊运动,正常饲养,过度运动组小鼠进行过度训练,常规运动组小鼠在与过度运动组相同的游泳箱中每天进行30 min的游泳训练,持续7 d,测定心系数、收缩压、心率、血浆心钠索、ET、Ang、NO、NOS等指标。结果:和对照组相比,常规运动组和过度运动组小鼠的心脏系数/体重指数变化具有显著性统计学意义。运动后常规运动组和过度运动组的平均血浆心钠素水平均非常显著高于运动前,运动前后常规运动组的平均血浆心钠素量也分别显著高于过度运动组。与对照组相比,常规运动组ET具有显著性差异,Ang具有极显著性差异,过度运动组的Ang显著低于常规运动组。常规运动组与过度运动组与对照组相比,NO、NOS活性均有非常显著性差异,过度运动组小鼠NO活性显著低于常规运动组小鼠,过度运动组小鼠NOS活性低于常规运动组小鼠,但无显著性差异。结论:过度运动状态下,小鼠体内分泌各指标值降低,内分泌系统活力大大降低,紊乱程度增大,使得小鼠机体功能大大减弱。
[Abstract]:Objective: to analyze the overtraining mice endocrine symptoms characteristics. Methods: the mice were randomly divided into blank control group, routine exercise group, exercise group over three groups, 10 mice in each group. The control group every day without any special movement, normal feeding, excessive movement of mice in excessive training, regular exercise in swimming mice the same box and excessive exercise group for 30 min every day in the swimming training for 7 d, the determination of heart coefficient, systolic blood pressure, heart rate, plasma heart sodium cable, ET, Ang, NO, NOS and other indicators. Results: compared with the control group, with statistically significant changes in BMI / conventional transport coefficient of heart dynamic group and overtraining mice after exercise. The average plasma water routine exercise group and exercise group over the average was significantly higher than that before exercise, the average amount of plasma atrial natriuretic peptide before and after exercise routine exercise group were also significantly higher than that of excessive The exercise group compared with control group, routine exercise group ET has significant difference, Ang has a very significant difference, excessive exercise group Ang was significantly lower than that of conventional exercise group. Routine exercise group compared with exercise group and control group NO, NOS activity showed significant difference, excessive exercise group were significant NO activity less than normal mice, excessive exercise group the activity of NOS in mice is lower than that of the normal mice, but there was no significant difference. Conclusion: the excessive motion state, in vivo secretion index decreased, the activity of the endocrine system is greatly reduced, the degree of disorder increases, greatly weakened the body function in mice.

【作者单位】：贵阳护理职业学院卫生管理系;
【分类号】：R87

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