多频域后处理图像对计算机辅助检测数字胸片上肺结节能力的影响

发布时间：2018-04-15 23:39

本文选题：肺肿瘤 + 数字影像　；参考：《中国医学影像技术》2015年02期

【摘要】：目的评价多频域后处理数字胸片图像对计算机辅助检测系统输出结果的影响。方法选择经CT证实正常248名受检者的DR后前位胸片和30例有肺结节的DR后前位胸片,并应用Philips UNIQUE软件对其进行高频、低频处理。由2名10年以上经验的放射科医生结合CT图像阅读胸片,二人意见达成一致后,在数字化胸片上标记结节位置,保存标记结果并将其作为金标准。然后由CAD系统阅读后处理图像,由2名医师评价CAD系统在后处理图像上肺结节检测的假阳性区域和敏感度。结果 CAD系统在248例低频、常规和高频图像上分别显示了715、585和286个可疑区域,平均每例检出的假阳性区域分别为2.88个、2.36个和1.15个,3组图像检测的假阳性区域及组间差异均具有统计学意义。30例DR图像上共有38个金标准结节,CAD系统在低频、常规和高频图像上分别检测到33、30、28个结节,其检测敏感度分别为86.84%、78.95%和73.68%,ROC曲线下面积分别为0.722、0.670和0.618,3组图像之间检测的差异无统计学意义。结论高频、低频和常规图像模式对CAD系统检测能力无明显影响,但其在低频、常规和高频图像中检测的假阳性有逐渐增高的趋势,肺结节检测敏感度有逐步下降的趋势。
[Abstract]:Objective to evaluate the effect of digital chest radiography in multi-frequency domain on the output of computer-aided detection system.Methods A total of 248 normal subjects were examined by CT and 30 patients with pulmonary nodules were examined by Philips UNIQUE software.Two radiologists with more than 10 years' experience read chest radiographs combined with CT images. After they reached an agreement, the nodule location was labeled on digital chest radiographs, and the results were preserved and taken as the gold standard.Then the post-processed images were read by CAD system, and the false positive areas and sensitivity of pulmonary nodules detected by CAD system were evaluated by two physicians.Results the CAD system showed 715585 and 286 suspicious areas on the low frequency, conventional and high frequency images of 248 cases, respectively.The average false-positive areas detected in each case were 2.88 false positive areas and 1.15 false positive areas respectively. There were statistically significant differences among the three groups. There were 38 gold standard nodule CAD systems in low frequency on 30 Dr images.33,30,28 nodules were detected on conventional and high frequency images respectively. The sensitivity was 86.84% and 73.68%, respectively. The area under the ROC curve was 0.722 ~ 0.670 and 0.61870, respectively. There was no significant difference between the two groups.Conclusion High frequency, low frequency and conventional image patterns have no significant influence on the detection ability of CAD system, but the false positive rate detected in low frequency, conventional and high frequency images is gradually increasing, and the sensitivity of pulmonary nodule detection is decreasing gradually.
【作者单位】：首都医科大学附属北京友谊医院放射科;
【基金】：2014年首都医科大学基础-临床科研合作基金
【分类号】：R734.2;R730.44

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