CTP评估周围型肺癌组织学类型、分期及肿瘤坏死的价值

发布时间：2018-04-19 11:22

本文选题：胸部CT + 灌注成像　；参考：《中国CT和MRI杂志》2016年04期

【摘要】：目的研究胸部C T灌注成像(CTP)对周围型肺癌组织学类型、分期及肿瘤坏死的评估价值。方法选取我院52例病理证实为周围型肺癌的患者为研究对象,CT观察大小、形态、密度等情况,计算患者CT灌注参数,包括灌注值(PER)、强化峰值(PE)、血容量(BV)、对比剂达峰值时间(TTP),分析不同组织学类型、分期以及肿瘤坏死患者的CT灌注值差异。结果临床分期:T1与T2比较,PER、PE、BV显著较高(P0.05),TTP显著较低(P0.05),T2与T3比较,PER、PE、BV显著较低(P0.05),而T2、T3患者TTP比较无统计学意义(P0.05);组织学类型:小细胞癌PER、PE、BV分别为(64.52±34.36)、(60.20±31.74)、(34.12±16.36)较高(P0.05),腺癌鳞癌,但比较均无统计学意义(P0.05);肿瘤坏死:未坏死组PER、PE、BV与坏死组比较显著较高(P0.05),TTP与坏死组比较显著较低(P0.05)。结论胸部CT灌注扫描对周围型肺癌患者分期、组织学类型及肿瘤坏死有一定的鉴别价值,尤其对于肿瘤是否出现坏死的反映明显,可为周围型肺癌早期诊断、术前分期及预后评价等提供重要的临床依据。
[Abstract]:Objective to study the value of CT perfusion imaging (CTP) in evaluating the histological type, staging and necrosis of peripheral lung cancer.Methods 52 patients with peripheral lung cancer confirmed by pathology were selected as the object of study. The CT perfusion parameters were calculated.It included Perot, PEV, BVV, TTPT. The difference of CT perfusion value among different histological types, stages and tumor necrosis patients was analyzed.However, there was no significant difference between the two groups (P 0.05) and tumor necrosis: PERP PEBV in the non-necrotic group was significantly higher than that in the necrotic group (P 0.05) and the TTP in the necrotic group was significantly lower than that in the necrotic group (P 0.05).Conclusion chest CT perfusion scan is valuable in differentiating the stage, histological type and tumor necrosis of peripheral lung cancer, especially for the early diagnosis of peripheral lung cancer.Preoperative staging and prognosis evaluation provide important clinical basis.
【作者单位】：湖北民族学院附属宜昌医院(宜昌市第二人民医院)放射科;
【分类号】：R734.2;R730.44

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