宝石能谱CT成像碘基图在肺栓塞诊断中的应用价值

发布时间：2018-04-20 06:22

本文选题：肺动脉栓塞 + 能谱CT　；参考：《新疆医科大学》2017年硕士论文

【摘要】：目的:探讨宝石能谱CT成像碘基图在肺栓塞中的诊断价值。方法:对某院2015年1月-2016年5月间临床高度怀疑肺动脉栓塞的80例患者行宝石能谱增强扫描,在CT肺血管造影图像(CTPA)图像上确诊肺栓塞20例,通过数据后处理,获得常规CTPA图像及碘基物质图像。在CTPA图像上观察肺动脉内栓子的分布情况,记录栓子的分布、数目及栓子类型;分析不同类型栓子引起供血区的碘含量变化。利用GSI Viewer软件包定量测定正常肺组织的碘含量与栓塞区肺组织的碘含量值,并进行比较,采用配对t检验及符号秩检验;计量资料比较采用x2检验。结果:经CTPA图像上确诊肺栓塞的20例患者,共发现101个栓子,其中肺叶栓子25个,肺段栓子59个,亚段栓子17个;完全型栓子60个,不完全型栓子41个,不完全型栓子中包括中心型栓子6个、偏心型栓子30个、附壁型栓子5个;栓塞区与对照区碘含量分别为[(9.56±5.96)g/L]和[(15.58±6.68)g/L],两者差异有统计学意义(p0.05);完全型栓子中栓塞区与对照区碘含量分别为[(6.22±3.60g)/L]和[(16.92±6.94)g/L],两者差异有统计学意义(p0.05),中心型栓子栓塞区与对照区碘含量分别为[(10.73±5.02)g/L]和[(12.54±5.72)g/L],两者差异无统计学意义;偏心型栓子栓塞区和对照区的碘含量分别为[(11.18±5.82)g/L]和[(14.33±6.18)g/L],两者差异有统计学意义(p0.05);附壁型栓子栓塞区和对照区的碘含量分别为[(18.47±7.02)g/L]和[(18.62±7.90)g/L],两者差异无统计学意义。结论:宝石能谱CT能够显示肺栓塞时肺功能的改变,分析不同类型栓子对供血区域肺血流的影响,对肺栓塞的病情评估具有重要的临床应用价值。
[Abstract]:Objective: to evaluate the diagnostic value of gemstone energy dispersive CT imaging iodide in pulmonary embolism. Methods: 80 patients with pulmonary embolism who were clinically suspected from January 2015 to May 2016 in a hospital were examined with enhanced gemstone energy spectrum. Twenty patients were diagnosed with pulmonary embolism on CT pulmonary angiography (CTPA) images. Conventional CTPA images and iodized substance images were obtained. The distribution of emboli in pulmonary artery was observed on CTPA images, the distribution, number and type of emboli were recorded, and the changes of iodine content in blood supply areas caused by different types of emboli were analyzed. The contents of iodine in normal lung tissue and lung tissue in embolic area were quantitatively measured by GSI Viewer software package, and compared, paired t test and symbolic rank test were used, and the measurement data were compared by x2 test. Results: a total of 101 emboli were found in 20 patients with pulmonary embolism diagnosed by CTPA images, including 25 pulmonary lobe emboli, 59 pulmonary emboli, 17 subsegmental emboli, 60 complete emboli and 41 incomplete emboli. The incomplete type included 6 central type emboli, 30 eccentric type emboli and 5 wall type emboli. The contents of iodine in embolization area and control area were [9.56 卤5.96)g/L] and [15.58 卤6.68)g/L], respectively, the difference was statistically significant (p0.05), the iodine content in embolized area and control area was [6.22 卤3.60g)/L] and [16.92 卤6.94)g/L] in complete embolism, the difference was significant (p0.05). The contents of iodine in the irradiated area were [10.73 卤5.02)g/L] and [12.54 卤5.72)g/L], respectively. There was no significant difference between the two groups. The contents of iodine in eccentric embolism and control were [11.18 卤5.82)g/L] and [14.33 卤6.18)g/L], respectively, the difference was significant (P < 0.05), the contents of iodine in embolic zone and control area were [18.47 卤7.02)g/L] and [18.62 卤7.90)g/L], respectively, and there was no significant difference between them. Conclusion: EDS CT can show the changes of pulmonary function in pulmonary embolism, and analyze the influence of different types of emboli on the pulmonary blood flow in the blood supply area, which has important clinical application value in evaluating the condition of pulmonary embolism.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R563.5;R816.41

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