数字乳腺断层融合X线成像中平均腺体剂量与乳腺密度、压迫厚度的关系

发布时间：2018-04-23 00:10

  本文选题：数字乳腺断层融合X线成像 + 放射摄影术　； 参考：《放射学实践》2017年05期

【摘要】：目的:探讨数字乳腺断层融合X线成像(DBT)中平均腺体剂量(AGD)与乳腺密度、压迫厚度的关系。方法:搜集在DBT Combo模式[即DBT和全视野数字化乳腺摄影(FFDM)分别在同一乳腺、在同一压迫厚度下进行摄影]下行双侧乳腺摄影的女性患者271例。分析共542幅DBT和542幅FFDM的单侧乳腺头尾位图像。结果:(1)压迫厚度与AGD_(DBT)呈正向较强相关(r=0.920,P0.001),乳腺密度与AGD_(DBT)呈正向较弱相关(r=0.263,P0.001)。压迫厚度和乳腺密度分别是AGD_(DBT)的独立影响因素(B_(压迫厚度)=0.046,B_(乳腺密度)=0.084,P0.001)。压迫厚度对AGD_(DBT)的影响较乳腺密度大(压迫厚度、乳腺密度的标准化系数分别为0.940、0.143)。(2)压迫厚度与△AGD(AGD_(DBT)减去AGD_(FFDM))呈负向较弱相关(r=-0.287,P0.001),乳腺密度与△AGD呈负向中等相关(r=-0.616,P0.001);乳腺密度和压迫厚度分别是△AGD的独立影响因素(B_(压迫厚度)=-0.012,B_(乳腺密度)=-0.219,P0.001);乳腺密度对△AGD的影响较压迫厚度大(压迫厚度、乳腺密度的标准化系数分别为-0.580、-0.366)。(3)在乳腺密度75%且压迫厚度为56~75mm和76~95mm时,AGD_(DBT)均值低于AGD_(FFDM),差异有统计学意义(P0.05)。在乳腺密度为25%~50%且压迫厚度为76~95mm时,AGD_(DBT)均值与AGD_(FFDM)相仿(P0.05)。在乳腺密度为51%~75%且压迫厚度为56~75mm时,AGD_(DBT)均值与AGD_(FFDM)相仿(P0.05)。在其他乳腺密度和压迫厚度分层中(压迫厚度均≤95mm),AGD_(DBT)均值高于AGD_(FFDM),差异有统计学意义(P0.05)。结论:AGD_(DBT)与乳腺密度、压迫厚度呈正相关,压迫厚度对AGD_(DBT)的影响更大。△AGD与乳腺密度、压迫厚度呈负相关;乳腺密度对△AGD的影响更大。在乳腺密度75%且压迫厚度为56~95mm时,AGD_(DBT)均值低于AGD_(FFDM);在其他乳腺密度及压迫厚度分层(压迫厚度均≤95mm)中,AGD_(DBT)均值高于或等于AGD_(FFDM)。
[Abstract]:Objective: to investigate the relationship between the average glandular dose (AGD) and breast density and compression thickness in digital mammographic fusion X ray imaging (DBT). Methods: a total of 271 female patients underwent bilateral mammography under DBT Combo mode (DBT and full field digital mammography FFDM) under the same mammary gland and under the same compression thickness respectively. A total of 542 DBT and 542 FFDM images of unilateral breast head and tail were analyzed. Results (1) the thickness of compression was positively correlated with AGD / D) and the density of mammary gland was positively correlated with the density of AGD / D (0.263 / P 0.001), and the density of mammary gland was positively correlated with the density of AGD / D / DBT. The thickness of compression and density of breast are independent influencing factors of AGD _ S _ D _ D _ D _ D _ D _ D _ D _ D _ D _ D _ D _ D _ D _ D _ D _ D _ (DBT). The effect of compression thickness on AGD _ D _ D _ D _ DBT is greater than that on breast density. The normalized coefficient of density of mammary gland is 0.940 / 0.143, respectively) the density of breast is negatively correlated with the thickness of AGD / D / D / D / D (DBT) minus AGD / D / D / D / D), the density of mammary gland is negatively correlated with AGD, r -0.616 / P / 0.001, and the density and thickness of breast are independent influencing factors of AGD, respectively. The effect of breast density on AGD is greater than that on compressed thickness. The standard coefficient of breast density was -0.580 ~ (-0.366n)) when the density of mammary gland was 75% and the compression thickness was 56~75mm and 76~95mm, the mean value of 76~95mm was lower than that of 56~75mm / FFDM. The difference was statistically significant (P 0.05). When the density of mammary gland is 25% and the thickness of compression is 50%, the average value of 76~95mm is similar to that of 76~95mm. When the density of mammary gland is 51% and the compression thickness is 56~75mm, the average value of 56~75mm is similar to that of 56~75mm. In other layers of breast density and compression thickness (compression thickness 鈮，

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