颅内动脉分叉部血管结构与分叉部动脉瘤形成的相关性研究

发布时间：2018-05-03 08:19

本文选题：数字减影血管成像 + 血流动力学　；参考：《心脑血管病防治》2015年05期

【摘要】：目的通过回顾性采集颅内动脉分叉部的血管形态几何参数,分析血管结构与动脉瘤发生的相关性,为后期前瞻性研究提供理论依据。方法通过回顾确诊颅内动脉瘤的病例资料,得到可以进行颈内-后交通动脉分叉部分叉角、颈内动脉和后交通动脉直径测量的颈内-后交通动脉分叉部动脉瘤共14例为研究组,非颈内-后交通动脉分叉部动脉瘤共15例为对照组。分别测量两组的颈内-后交通动脉分叉部分叉角(Ap),后交通动脉直径(Dp),颈内动脉C6段(DC6)与C7段直径(DC7),统计分析颈内-后交通动脉分叉部血管形态几何参数与动脉瘤发生的相关性。结果研究组颈内-后交通动脉分叉部分叉角明显小于对照组(P0.01)。根据分叉角进行分层,对分叉角在84°至120°的病例,进行颈内-后交通动脉分叉部血管直径的第二次统计分析,结果显示研究组的后交通动脉直径明显小于对照组(P0.05);研究组后交通动脉与C6段直径比值明显小于对照组(P0.05)。结论颈内-后交通动脉分叉部分叉角的大小与颈内-后交通动脉分叉部动脉瘤的形成相关,分叉角越小越有可能形成动脉瘤;而在一定分叉角范围内,后交通动脉与颈内动脉直径的比值与颈内-后交通动脉分叉部动脉瘤的形成具有相关性,比值越小越有可能形成动脉瘤。
[Abstract]:Objective to analyze the correlation between angiostructures and aneurysms by collecting the morphological and geometric parameters of the bifurcation of intracranial arteries, and to provide a theoretical basis for the prospective study in the later stage. Methods by reviewing the data of patients with intracranial aneurysms, 14 cases of internal and posterior communicating artery bifurcation aneurysms were obtained in the study group. The internal and posterior communicating artery diameters of internal carotid artery and posterior communicating artery were measured. 15 cases of non-internal-posterior communicating artery bifurcation aneurysms were used as control group. The diameters of the internal and posterior communicating arteries of the internal carotid artery (C6 segment DC6) and the internal carotid artery (DC6 segment DC6) and the diameter of the C7 segment of the internal carotid artery (C7) were measured, respectively. The relationship between the morphological and geometric parameters of the bifurcation of the internal and posterior communicating artery and the occurrence of aneurysms was analyzed statistically. Results the forked angle of the internal-posterior communicating artery in the study group was significantly lower than that in the control group (P 0.01). According to the bifurcation angle, the second statistical analysis was made on the diameter of the bifurcation part of the internal posterior communicating artery in the patients with the bifurcation angle from 84 掳to 120 掳. The results showed that the diameter of the posterior communicating artery in the study group was significantly smaller than that in the control group (P 0.05), and the ratio of the diameter of the posterior communicating artery to the C6 segment in the study group was significantly smaller than that of the control group (P 0.05). Conclusion the size of the forked part of the internal and posterior communicating artery is related to the formation of the aneurysm in the bifurcation part of the internal and posterior communicating artery, and the smaller the angle of bifurcation is, the more likely it is to form the aneurysm, but within a certain range of bifurcation angles, The ratio of the diameter of the posterior communicating artery to the internal carotid artery is correlated with the formation of the bifurcation aneurysm of the internal and posterior communicating artery, and the smaller the ratio is, the more likely it is to form the aneurysm.
【作者单位】：浙江大学医学院附属第一医院神经外科;
【基金】：浙江省卫生厅科技计划项目(编号:2008A055)
【分类号】：R743.3

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