即刻种植和延期种植后种植体周围骨质变的锥形束CT的对比研究

发布时间：2018-05-10 12:14

本文选题：骨小梁 + 空间结构　；参考：《大连医科大学》2012年硕士论文

【摘要】：目的：利用锥形束CT(CBCT)影像分析来比较即刻种植和延期种植后种植体周围的骨质变化。材料和方法：实验动物选用24月龄雄性杂种犬六条，体重10-15公斤。麻醉下拔除实验犬双侧上颌第三切牙（I3），第3和第4下颌前磨牙（P3和P4），每个P3近中拔牙窝和P4远中拔牙窝被选定为实验组，而其余拔牙窝作为不进行干预自然愈合的对照组。种植体植入区域会随机接受如下治疗方案中的一种：(1)即刻种植（IIP）和即刻负重（IL）组;（2）延期种植（DIP）和延期负重（DL组）;（3）延期种植（DIP）和即刻负重（IL）组;（4）对照组（拔牙窝自然愈合）。最终处死实验犬，取材、固定，在选定ROI区域范围内利用CBCT进行三维重建得到骨小梁空间结构的计算机三维图形，对样本进行三维评测，指标包括：骨体积（BV），组织体积(TV)，骨体积分数（BV/TV）,骨表面积（BS），骨表面积体积比（BS/BV），骨小梁厚度（Tb.Th），骨小梁间隙（Tb.Sp），骨小梁数目（Tb.N），，结构模型指数（SMI），骨小梁模式因子（TbPf），分形维数（FD）和Conn.D.连接密度。结果：分析结果表明IIP+IL, DIP+IL和DIP+DL实验组样本中的骨表面积体积比（BS/BV）、分形维数（FD）、骨小梁间隙（Tb.Sp）和接触密度(Conn.Dn)与对照组有明显差异（P0.05）。其中所有实验组骨表面积体积比（BS/BV）和接触密度(Conn.Dn)比对照组均数数值差异明显高，分形维数（FD）和骨小梁间隙（Tb.Sp）比对照组均数数值差异明显低。而三组实验组之间的比较：IIP+IL vs.DIP+IL; IIP+IL vs. DIP+DL; DIP+IL vs. DIP+DL.之间无明显差异（P0.05）。结论: 1.该动物实验结果表明与非种植区相比，种植体周围骨的质量显著提高。 2.即刻种植即刻负重（IIP+IL）、延期种植延期负重（DIP+DL）、延期种植即刻负重（DIP+IL）三种治疗方案中种植体周围骨无差异。
[Abstract]:Aim: to compare the changes of bone around implants after immediate implantation and delayed implantation by CT-CBCT image analysis. Materials and methods: six 24-month-old male hybrid dogs weighing 10-15 kg were used. The third and fourth mandibular premolars were extracted under anesthesia. The third and fourth mandibular premolars were selected as the experimental group. Each P3 proximal extraction fossa and P4 distal extraction fossa were selected as the experimental group, while the other extraction fossa were used as the control group without intervention in natural healing. Implants were randomly assigned to one of the following treatments: 1) immediate implant (IIP1) and 2) immediate weight bearing (ILL) group) and 2) delayed implant group (DIP3) and (2) DIP3) group) and 4) control group (natural healing of tooth extraction nest). Finally, the experimental dogs were killed, the specimens were taken and fixed, and the three-dimensional reconstruction of the bone trabecular space structure was made by using CBCT within the selected ROI area, and the three-dimensional evaluation of the samples was carried out. The indexes include: bone volume, tissue volume, bone volume fraction, bone surface area, bone surface area ratio, bone trabecular thickness, trabecular space, bone trabecular number, Tb.N, structural model index, trabecular pattern factor TbPfU, fractal dimension FDD and Conn.D. Connection density. Results: the results showed that the volume ratio of bone surface area of IIP IL, DIP IL and DIP DL group was significantly different from that of control group (P 0.05). The fractal dimension of bone surface area and bone trabecular space (Tb.Spn) and contact density (Conn.Dn) were significantly different from those of control group (P < 0.05). The bone surface area ratio (BS / BV) and contact density (Conn.Dn) of all experimental groups were significantly higher than those of the control group, and the fractal dimension (FDD) and trabecular space (TB. Sp) were significantly lower than those of the control group. The comparison among the three experimental groups was made between the three groups: IIP IL vs.DIP IL; IIP IL vs. DIP DL; DIP IL vs. DIP DL. There was no significant difference between the two groups (P 0.05). Conclusion: 1. The results of the animal experiment showed that the quality of bone around the implant was significantly higher than that in the non-implant area. 2. There was no difference in the periimplant bone among the three treatments: immediate implantation of IIP ILA, delayed implantation of DIP DLX, and delayed implantation of immediate load bearing DIP.
【学位授予单位】：大连医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R816.98

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