低剂量CT灌注成像在脑梗死患者恢复期的应用

发布时间：2018-05-12 09:31

本文选题：脑梗死 + 低辐射剂量　；参考：《实用医学杂志》2015年13期

【摘要】：目的:研究低剂量CT灌注成像显示脑梗死患者恢复期阶段梗死灶脑细胞活性的诊断价值。方法:选取50例临床诊断为大面积脑梗死的患者,在脑梗死恢复期随机分成两组,在做常规平扫基础上分别行常规剂量(120 k V、200 m As)和低剂量(80 k V、200 m As)螺旋CT灌注扫描成像,由2名影像科资深专家评价图像并做出正确的诊断。结果:CT灌注成像除可以发现常规CT平扫和增强平扫能发现的陈旧性梗死灶外,还可以发现明显的梗死区周围局部血流增加现象。低剂量组所接受的辐射剂量远低于常规剂量,低剂量与常规剂量CT灌注成像下梗死中心区、缺血区各灌注参数值比较差异无统计学意义(P0.05)。结论:低剂量CT灌注成像在降低辐射剂量的同时可较好地评价梗死区局部血流灌注改善程度,对临床判断预后及治疗有着重要的意义。
[Abstract]:Objective: to study the diagnostic value of low dose CT perfusion imaging in the diagnosis of cerebral infarction in convalescent stage. Methods: fifty patients with large area cerebral infarction were selected and randomly divided into two groups during the convalescence of cerebral infarction. On the basis of routine plain scan, the conventional CT perfusion imaging was performed at the dose of 120kV / 200mAsand low dose of 80kV / 200mAsrespectively. The images were evaluated by two senior experts in the department of imaging and correct diagnosis was made. Results in addition to conventional CT plain scan and enhanced CT perfusion imaging, the old infarct foci could be found as well as the increased regional blood flow around the infarct area. The radiation dose in the low dose group was much lower than that in the conventional dose group. There was no significant difference in the perfusion parameters of the infarct center and ischemic area between the low dose group and the conventional dose CT perfusion imaging group (P 0.05). Conclusion: low dose CT perfusion imaging can reduce the radiation dose and evaluate the improvement of regional blood flow perfusion in the infarcted area, which is of great significance for clinical prognosis and treatment.
【作者单位】：广东省兴宁市人民医院放射科;
【分类号】：R743.3;R816.1

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