ROC曲线评价双源CT小肠造影对克罗恩病活动性评估的诊断价值

发布时间：2018-05-30 23:40

本文选题：CTE + 克罗恩病　；参考：《临床放射学杂志》2015年11期

【摘要】：目的探讨双源CT口服法小肠CT造影(CTE)检查对克罗恩病(CD)活动性评估的应用价值。方法回顾性分析116例确诊为CD患者的CTE影像资料,评估患者肠壁异常增厚,肠黏膜异常强化,肠腔狭窄,木梳征,肠系膜增大的淋巴结,动脉期肝脏异常灌注,瘘道、溃疡及脓肿等情况,并进行CTE综合评分。以临床活动性(基于CD活动性指数、血清炎性指标、内镜检查)作为金标准,应用ROC曲线分析CTE综合评分对CD活动性判断的诊断效能及最佳诊断分界值。结果 ROC曲线分析示曲线下面积(AUC)为0.881(P=0.000),最佳诊断分界值为6分,CTE综合评分≥6分时,CTE诊断CD处于活动期,敏感度为80.8%,特异度为83.3%,误诊率为16.7%。结论CTE综合评分方法对于CD的活动性判断有较高的诊断效能。
[Abstract]:Objective to evaluate the diagnostic value of dual source CT oral enterography (CTE) in evaluating the activity of Crohn's disease (Crohn's disease). Methods the CTE imaging data of 116 patients with CD were retrospectively analyzed. The abnormal thickening of intestinal wall, abnormal enhancement of intestinal mucosa, stenosis of intestinal cavity, wood comb sign, enlarged lymph nodes of mesentery, abnormal hepatic perfusion and fistula in arterial phase were evaluated. Ulcers and abscesses were evaluated by CTE. Clinical activity (based on CD activity index, serum inflammatory index, endoscopy) was used as gold standard. ROC curve was used to analyze the diagnostic efficacy and optimal diagnostic threshold of CTE comprehensive score for CD activity. Results the ROC curve analysis showed that the area under the curve was 0.881p 0.000, and the best diagnostic threshold was that the diagnostic CD was active, sensitivity was 80.8, specificity was 83.3 and the misdiagnosis rate was 16.7when the comprehensive score of CTE was 6 minutes or more. Conclusion the CTE comprehensive scoring method has high diagnostic efficacy in the diagnosis of CD activity.
【作者单位】：南方医科大学南方医院影像中心;南方医科大学南方医院消化内科;南方医科大学生物统计学系;
【分类号】：R574.62;R816.5

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