核磁共振弥散加权成像对局部晚期食管癌放疗靶区勾画的作用

发布时间：2018-06-02 12:57

本文选题：核磁共振 + 弥散加权　；参考：《西安交通大学学报(医学版)》2017年04期

【摘要】：目的研究DWI影像联合T2WI影像与CT影像融合技术的价值,探讨DWI影像对晚期食管癌放射治疗靶区范围确定的作用。方法 23例局部晚期食管癌单纯放疗病例,采用放疗所需体位及固定方法,同时对患者进行CT定位扫描、T2WI及DWI定位扫描。将获得的3个序列影像经网络传输至Eclipse治疗计划系统,使用治疗计划系统的归一化信息自动融合法对影像进行融合。由放疗医师分别在CT影像和CT与DWI融合影像上对靶区范围进行勾画。应用治疗计划系统的图像融合功能及统计功能对两种影像确定的靶区进行评价。结果以CT影像为参考确定的食管癌靶区体积及长度,相对于以CT和DWI融合图像为参考确定的食管癌靶区体积及长度之间具有明显差异;临床医师应用CT与DWI融合图像勾画的食管癌靶区体积及长度结果3个组之间更为接近。结论 DWI与CT融合图像能清楚地反映肿瘤靶区的范围,对局部晚期食管癌的靶区确定有良好的辅助作用。
[Abstract]:Objective to study the value of DWI combined with T2WI and CT image fusion, and to explore the role of DWI in determining the target area of radiotherapy for advanced esophageal carcinoma. Methods Twenty-three patients with locally advanced esophageal carcinoma were treated with radiotherapy alone. Both CT scanning and DWI scanning were performed. The three sequence images were transferred to the Eclipse treatment planning system via the network, and the image fusion was performed by using the normalized information fusion method of the treatment plan system. The target area was delineated by radiologists on CT images and CT / DWI fusion images. The image fusion function and statistical function of the treatment planning system were used to evaluate the target areas determined by the two images. Results the volume and length of esophageal cancer target area determined by CT images was significantly different from that of esophageal carcinoma target area determined by CT and DWI fusion images. The volume and length of the target area of esophageal carcinoma delineated by CT and DWI fusion images were closer to each other. Conclusion the fusion images of DWI and CT can clearly reflect the range of tumor target area and play a good role in determining the target area of local advanced esophageal carcinoma.
【作者单位】：西安交通大学医学部附属陕西省肿瘤医院放射治疗科;西安交通大学医学部附属陕西省肿瘤医院妇科肿瘤科;
【基金】：陕西省自然科学基金资助项目(No.2014JM4191)~~
【分类号】：R730.55;R735.1

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