急、慢性有氧运动对白介素的影响

发布时间：2018-06-21 20:50

本文选题：有氧运动 + 免疫系统　；参考：《河南师范大学学报(自然科学版)》2015年05期

【摘要】：目的:观察急、慢性有氧运动后大鼠血液白介素IL-2和IL-6的变化情况,探讨运动后白介素的应答、适应性反应.方法:120只3月龄SD大鼠随机分为急性运动组和四周运动组,跑台速度为25m/min的恒定负荷.各组运动前、运动后即刻和运动后3h取血,采用放射免疫法检测大鼠血液中IL-2和IL-6的变化情况.结果:1、一次急性运动后,与安静对照组相比,IL-6的浓度在运动后即刻、运动后3h均出现升高的趋势,但没有统计学意义(P0.05).IL-2浓度的变化与IL-6相似,运动后即刻有所下降,3h后虽有回升,但无统计学意义(P0.05).2、4周有氧耐力运动对白介素的影响:1周有氧耐力训练后,WK1-B,WK1-A,WK1-3h与C组相比,大鼠血液中IL-6的浓度显著升高,差异非常显著(P0.01).WK1-3h组与WK1-B组相比,IL-2的浓度有明显升高(P0.05),而与WK1-A组相比,有非常显著性差异(P0.01).有氧耐力运动两周后,WK2-B,WK2-A和WK2-3h组大鼠的IL-6水平与C组有显著的升高(P0.05).两周的有氧耐力使IL-2浓度在WK2-B组较C组有明显的升高现象,差异非常显著(P0.01).WK2-A组与C组相比,IL-2浓度变化不明显(P0.05).WK2-3h组与WK2-B组相比,IL-2浓度有显著升高(P0.05)第三周和第四周大鼠IL-2和IL-6的浓度变化不明显,与安静对照组相比,没有显著性差异(P0.05).结论:一次性有氧运动对大鼠白介素的影响不明显,白介素在急性运动后的变化情况与运动强度大小可能有关.周期性有氧耐力训练促进大鼠机体产生良好的适应性,白介素呈"升高-下降"的变化趋势,1-2周是免疫应激阶段,3-4周大鼠机体实现了良好的免疫调节,处于适应阶段.
[Abstract]:Aim: to observe the changes of interleukin-2 (IL-2) and interleukin-6 (IL-6) in blood of rats after acute and chronic aerobic exercise. Methods 120 3 month old SD rats were randomly divided into acute exercise group and peripheral exercise group. The treadmill speed was the constant load of 25m/min. Before exercise, immediately after exercise and 3 hours after exercise, the changes of IL-2 and IL-6 in blood of rats were detected by radioimmunoassay. Results after one acute exercise, compared with the quiet control group, the concentration of IL-6 increased immediately after exercise and 3 hours after exercise, but there was no statistically significant difference in the concentration of IL-6 between P0.05U. IL-2 and IL-6. Although there was an increase after 3 hours of exercise, there was no significant difference in the effect of aerobic endurance exercise for 4 weeks on interleukin. After 1 week of aerobic endurance training, the concentration of IL-6 in blood of rats in group C was significantly higher than that in group C. Compared with WK1-B group, the concentration of IL-2 was significantly increased in P0.01U. WK1-3h group and WK1-A group, but there was a very significant difference between WK1-A group and WK1-B group. After two weeks of aerobic endurance exercise, IL-6 levels in WK2-BUWK2-A and WK2-3h groups were significantly higher than those in group C (P 0.05). After two weeks of aerobic endurance, IL-2 concentration in WK2-B group was significantly higher than that in C group. There was no significant difference in the concentration of IL-2 between group P0.01A and group C (P0.05U. WK2-3h) compared with WK2-B group, the concentration of IL-2 increased significantly (P0.05) at the third week and the fourth week, there was no significant difference in the concentration of IL-2 and IL-6 between group A and group C, and there was no significant difference in the concentration of IL-2 and IL-6 between group A and group C (P 0.05). Conclusion: the effect of one-off aerobic exercise on interleukin in rats is not obvious. The changes of interleukin after acute exercise may be related to the intensity of exercise. The periodic aerobic endurance training promoted the rats to produce good adaptability, and the change trend of interleukin was "rising and decreasing". The immune stress period was 3-4 weeks and the rats achieved good immune regulation and were in the adaptive stage.
【作者单位】：郑州大学体育系;
【基金】：国家社科基金青年项目(13CTY024) 2013年河南省科技厅重点科技攻关项目“862激光中频治疗法在高水平篮球运动员运动损伤治疗中的应用”(132102310437)
【分类号】：R87

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