宝石能谱CT在鉴别恶性胸腺瘤和纵隔淋巴瘤中的价值

发布时间：2018-07-03 03:16

本文选题：淋巴瘤 + 恶性胸腺瘤　；参考：《山西医科大学》2013年硕士论文

【摘要】：目的：通过测量和分析恶性胸腺瘤及纵隔淋巴瘤患者不同单能量下病变部位单能量图像的CT值及碘水含量、水含量,探讨CT能谱成像在鉴别恶性胸腺瘤和纵隔淋巴瘤中的价值。方法：回顾性分析行能谱CT检查并经手术切除或穿刺活检证实的的恶性胸腺瘤20例及纵隔淋巴瘤15例,在手术或穿刺活检前,均运用宝石能谱CT的能谱扫描模式进行平扫及增强扫描,图像在能谱成像浏览器(GSI viewer)软件下观察,运用分析工具分析病变部位的能谱曲线,测量不同单能量(40keV-140keV)下的CT值,并在物质分离图像上测量病变部位的碘含量及水含量,对数据进行分析及独立样本t检验。结果：平扫时恶性胸腺瘤组在40-50KeV能量水平的CT值明显低于纵隔淋巴瘤组,而在90-140KeV能量水平的CT值明显高于纵隔淋巴瘤组,差异有统计学意义。恶性胸腺瘤组能谱曲线斜率(0.23±0.06)明显低于纵隔淋巴瘤组(0.36±0.07),差异有统计学意义(t=2.681,p=0.012)。增强扫描后恶性胸腺瘤组在40-100KeV能量水平的CT值明显高于纵隔淋巴瘤组,差异有统计学意义；恶性胸腺瘤组能谱曲线斜率(1.32±0.42)明显低于纵隔淋巴瘤组(1.01±0.1),差异有统计学意义(t=2.681,p=0.015)。恶性胸腺瘤组的碘含量(1.75±0.53)g/L、水含量(1042.38±5.02)g/L明显高于纵隔淋巴瘤组(1.34±0.19)g/L,(1036.50±7.08)g/L差异亦有统计学意义。结论：宝石CT的能谱成像技术可以进行单能量能谱衰减曲线分析和碘含量、水含量分析,对恶性胸腺瘤及纵隔淋巴瘤的鉴别有一定意义。 CT能谱成像技术操作简便,能够广泛应用于临床。
[Abstract]:Objective: to measure and analyze the CT value and iodine water content of lesions in patients with malignant thymoma and mediastinal lymphoma under different single energy. To study the value of CT energy spectrum imaging in differentiating malignant thymoma from mediastinal lymphoma. Methods: twenty cases of malignant thymoma and 15 cases of mediastinal lymphoma confirmed by excision or puncture biopsy were analyzed retrospectively. The scanning mode of gem energy spectrum CT was used for plain scan and enhancement scan. The image was observed by the software of energy spectrum imaging browser (GSI viewer). The spectral curve of lesion was analyzed by means of analysis tools, and the CT value of different single energy (40keV-140keV) was measured. The iodine content and water content of the lesion were measured on the material separation image, and the data were analyzed and independent sample t-test. Results: the CT value of 40 ~ 50 KeV energy level in malignant thymoma group was significantly lower than that in mediastinal lymphoma group, but the CT value in 90-140 Kev energy level was significantly higher than that in mediastinal lymphoma group. The slope of energy spectrum curve in malignant thymoma group (0.23 卤0.06) was significantly lower than that in mediastinal lymphoma group (0.36 卤0.07). The CT value of 40 ~ 100 KeV energy level in malignant thymoma group was significantly higher than that in mediastinal lymphoma group, and the slope of energy spectrum curve in malignant thymoma group (1.32 卤0.42) was significantly lower than that in mediastinal lymphoma group (1.01 卤0.1). The iodine content (1.75 卤0.53) g / L and water content (1042.38 卤5.02) g / L in malignant thymoma group were significantly higher than those in mediastinal lymphoma group (1.34 卤0.19) g / L and (1036.50 卤7.08) g / L respectively. Conclusion: the single energy spectrum attenuation curve, iodine content and water content can be analyzed by the energy spectrum imaging technique of gemstone CT. It is useful for the differential diagnosis of malignant thymoma and mediastinal lymphoma. The technique of CT energy spectrum imaging is easy to operate and can be widely used in clinic.
【学位授予单位】：山西医科大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R730.44;R734.5;R736.3

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