延迟性肌肉酸痛与骨骼肌卫星细胞:骨骼肌损伤的修复
发布时间：2018-08-06 12:49
【摘要】：背景:长时间或高强度运动出现的骨骼肌纤维损伤是导致骨骼肌损伤直接原因。目的:文章从修复骨骼肌损伤的客观实际出发,提出骨骼肌损伤后产生的延迟性肌肉酸痛与骨骼肌卫星细胞之间存在某种关系。方法:检索1961年2月至2015年2月中国知网和Pub Med数据库中相关文献资料,中文检索词:延迟性肌肉酸痛;骨骼肌损伤;骨骼肌卫星细胞;调节因子;英文检索词:Delayed Onset Muscle Soreness;Satellite Cells,Skeletal Muscle;Myogenic Regulatory Factors。纳入59篇国内外文献,对骨骼肌损伤伴随的延迟性肌肉疼痛的发生机制做一探讨。结果与结论:骨骼肌微损伤主要涉及肌细胞生物膜、细胞骨架、肌小节、线粒体等超微结构的破坏和细胞代谢功能紊乱,进而导致骨骼肌收缩功能下降,期间常伴有延迟性肌肉酸痛,其中以离心运动对骨骼肌纤维的微细损伤最为显著;延迟性酸痛的骨骼肌特殊微环境一定程度上刺激骨骼肌卫星细胞生长因子的分泌,持续大强度离心运动引发的延迟性肌肉酸痛的发生时序与骨骼肌卫星细胞增殖时序存在一定的相关性。
[Abstract]:Background: skeletal muscle damage caused by long or high intensity exercise is a direct cause of skeletal muscle injury. Objective: from the objective reality of repairing skeletal muscle injury, the article proposed that delayed muscle pain after skeletal muscle injury and skeletal muscle satellite cells were related to some relationship. Methods: retrieval from February 1961 to 2015 2 Relevant literature in the Chinese knowledge network and the Pub Med database, Chinese retrieval words: delayed muscle pain, skeletal muscle injury; skeletal muscle satellite cells; regulatory factors; English retrieval words: Delayed Onset Muscle Soreness; Satellite Cells, Skeletal Muscle; Myogenic Regulatory, including 59 domestic and foreign documents, with skeletal muscle injury companion The mechanism of delayed muscle pain is discussed. Results and conclusions: skeletal muscle micro injury mainly involves the myosembrane, cytoskeleton, muscle segments, mitochondria and other ultrastructural damage and cell metabolic dysfunction, which leads to the decrease of skeletal muscle contraction function, which is often accompanied by delayed muscle soreness, which is transported by centrifugation. The micro injury of skeletal muscle fibers is the most significant. The special microenvironment of skeletal muscle in delayed pain stimulates the secretion of the growth factor of skeletal muscle satellite cell, and the time series of delayed muscle pain caused by continuous large intensity centrifugal movement has certain correlation with the time sequence of skeletal muscle satellite cell proliferation.
【作者单位】： 忻州师范学院体育系;
【基金】：忻州师范学院重点建设学科项目(xk201403)~~
【分类号】：R873
[Abstract]:Background: skeletal muscle damage caused by long or high intensity exercise is a direct cause of skeletal muscle injury. Objective: from the objective reality of repairing skeletal muscle injury, the article proposed that delayed muscle pain after skeletal muscle injury and skeletal muscle satellite cells were related to some relationship. Methods: retrieval from February 1961 to 2015 2 Relevant literature in the Chinese knowledge network and the Pub Med database, Chinese retrieval words: delayed muscle pain, skeletal muscle injury; skeletal muscle satellite cells; regulatory factors; English retrieval words: Delayed Onset Muscle Soreness; Satellite Cells, Skeletal Muscle; Myogenic Regulatory, including 59 domestic and foreign documents, with skeletal muscle injury companion The mechanism of delayed muscle pain is discussed. Results and conclusions: skeletal muscle micro injury mainly involves the myosembrane, cytoskeleton, muscle segments, mitochondria and other ultrastructural damage and cell metabolic dysfunction, which leads to the decrease of skeletal muscle contraction function, which is often accompanied by delayed muscle soreness, which is transported by centrifugation. The micro injury of skeletal muscle fibers is the most significant. The special microenvironment of skeletal muscle in delayed pain stimulates the secretion of the growth factor of skeletal muscle satellite cell, and the time series of delayed muscle pain caused by continuous large intensity centrifugal movement has certain correlation with the time sequence of skeletal muscle satellite cell proliferation.
【作者单位】： 忻州师范学院体育系;
【基金】：忻州师范学院重点建设学科项目(xk201403)~~
【分类号】：R873
【参考文献】
相关期刊论文 前10条
1 潘同斌;孙文杰;毛杉杉;王瑞元;;急性低氧及力竭运动对大鼠骨骼肌成肌调节因子MyoD和myogenin基因表达的影响[J];北京体育大学学报;2010年01期
2 何坚;王芗斌;廖军;王诗忠;;延迟性肌肉酸痛机制及中医药防治研究进展[J];福建中医药;2008年04期
3 张蔚菁;贾懿R，
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