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运动负荷对正常腰椎间盘MR扩散张量成像表现弥散系数和各向异性分数的影响

发布时间:2018-08-06 20:46
【摘要】:目的探讨运动负荷对正常腰椎间盘MR扩散张量成像(DTI)中表观弥散系数(ADC)和部分各向异性(FA)的影响。方法对30例健康志愿者行常规矢状位FSE/T2WI成像及运动负荷前后DTI成像,其中男性24名,女性6名,年龄19~25岁。在MR常规T2WI序列上对腰椎间盘按Pfirrmann标准进行退变分级,利用DTI原始数据重组b0图、ADC图及FA图,测量并比较运动负荷前后ADC值、FA值的变化。统计方法使用重复测量数据的方差分析,P0.05具有统计学意义。结果 30名志愿者,观测L1~S1共计150个椎间盘,将其中27例腰椎间盘Pfirrminn分级均为Ⅱ级的受试者纳入研究。腰椎间盘平均ADC值运动负荷前为(1.99±0.18)×10-3mm2/s,运动负荷后为(1.93±0.17)×10-3mm2/s,较运动负荷前下降,差异具有统计学意义(P0.05);腰椎间盘平均FA值运动负荷前为0.155±0.059,运动负荷后为0.163±0.017,较运动负荷前升高,差异不具有统计学意义(P0.05)。结论磁共振DTI成像可以定量分析运动负荷后腰椎间盘水分子扩散能力及各向异性程度的变化。运动负荷后,腰椎间盘ADC值下降,FA值升高,其中ADC值的变化更为敏感。
[Abstract]:Objective to investigate the effect of exercise load on the apparent diffusion coefficient (ADC) and partial anisotropic (FA) (FA) in diffusion Zhang Liang imaging (DTI) of normal lumbar disc. Methods routine sagittal FSE/T2WI imaging and DTI imaging before and after exercise load were performed in 30 healthy volunteers, including 24 males and 6 females aged 19 to 25 years. The lumbar intervertebral disc was graded according to Pfirrmann standard on conventional Mr T2WI sequence. The changes of ADC value and FA value before and after exercise load were measured and compared by recombination of b0 map and FA map using DTI original data. Statistical method using repeated measurement data analysis of variance (P0.05) has statistical significance. Results A total of 150 intervertebral discs were observed in 30 volunteers, 27 of whom were enrolled in the study with Pfirrminn grade 鈪,

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