双源CT评估冠状动脉狭窄对左室功能参数变化的影响
发布时间：2018-08-18 13:46
【摘要】：目的:应用双源CT探讨经临床诊断为冠心病的男性患者冠脉狭窄程度、支数及不同狭窄血管与左室功能指数（LVEF、LVSV、LVMM）改变之间的关系。方法:77例患者行双源CT（DSCT）冠脉CTA检查，使用Circulation软件对冠脉狭窄进行分析；使用CT Cardiac Function软件计算出左心室心肌质量（MM）、左心室每搏输出量（SV）、左心室射血分数（EF）值。分别对冠脉狭窄程度、狭窄支数、狭窄的不同血管与LVEF、LVSV、LVMM测量值改变之间的关系进行研究。结果:冠状动脉血管轻度与重度狭窄组、中度与重度狭窄组、单支与三支病变组及两支与三支病变组LVMM、LVSV、LVEF差异均有统计学意义（P0.05）；轻度与中度狭窄组及单支与两支血管病变组LVSV、LVEF差异无统计学意义（P0.05），LVMM值差异有统计学意义（P0.05）。当单支血管呈中、重度病变时，只有左前降支组LVMM、LVSV、LVEF值差异有统计学意义（P0.05）。结论:冠状动脉狭窄程度越重、狭窄支数越多对左心室功能损害越大，其中左前降支狭窄对左心室功能损害最大。冠状动脉狭窄时LVMM是较LVEF、LVSV更早期出现变化的指标。
[Abstract]:Objective: to investigate the relationship between the degree of coronary stenosis, number of coronary artery stenosis and the changes of left ventricular function index (LVMM) in male patients with coronary artery disease (CHD) by dual source CT. Methods 77 patients were examined with dual-source CT (DSCT) coronary CTA and analyzed by Circulation software, and the left ventricular ejection fraction (EF) of left ventricular mass (MM), (MM),) was calculated by CT Cardiac Function software. The relationship between the degree of coronary stenosis, the number of stenotic branches, the different vessels of stenosis and the changes of LVMM measured by LVEFN LVSVM were studied. Results: there were significant differences in LVMMV VEF between mild and severe coronary artery stenosis group, moderate and severe stenosis group, single vessel group and three vessel lesion group, and two vessel group and three vessel lesion group (P0.05). There was no significant difference in LVSVT LVEF between mild and moderate stenosis group and between single vessel group and two vessel disease group (P0.05). When the single vessel showed moderate or severe lesions, only the left anterior descending branch LVMMN LVSVE LVEF values were significantly different (P0.05). Conclusion: the more severe the coronary artery stenosis, the greater the left ventricular function damage caused by the number of stenosis branches, in which the left anterior descending branch stenosis is the most harmful to left ventricular function. LVMM is a more early indicator of changes in coronary artery stenosis than LVEFN LVSV.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R816.2
本文编号：2189651
[Abstract]:Objective: to investigate the relationship between the degree of coronary stenosis, number of coronary artery stenosis and the changes of left ventricular function index (LVMM) in male patients with coronary artery disease (CHD) by dual source CT. Methods 77 patients were examined with dual-source CT (DSCT) coronary CTA and analyzed by Circulation software, and the left ventricular ejection fraction (EF) of left ventricular mass (MM), (MM),) was calculated by CT Cardiac Function software. The relationship between the degree of coronary stenosis, the number of stenotic branches, the different vessels of stenosis and the changes of LVMM measured by LVEFN LVSVM were studied. Results: there were significant differences in LVMMV VEF between mild and severe coronary artery stenosis group, moderate and severe stenosis group, single vessel group and three vessel lesion group, and two vessel group and three vessel lesion group (P0.05). There was no significant difference in LVSVT LVEF between mild and moderate stenosis group and between single vessel group and two vessel disease group (P0.05). When the single vessel showed moderate or severe lesions, only the left anterior descending branch LVMMN LVSVE LVEF values were significantly different (P0.05). Conclusion: the more severe the coronary artery stenosis, the greater the left ventricular function damage caused by the number of stenosis branches, in which the left anterior descending branch stenosis is the most harmful to left ventricular function. LVMM is a more early indicator of changes in coronary artery stenosis than LVEFN LVSV.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R816.2
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