症状性下肢动脉疾病与肾动脉狭窄的相关性
发布时间：2018-08-20 17:54
【摘要】：目的：探讨症状性下肢外周动脉疾病(PAD)患者合并肾动脉狭窄的患病率及其相关因素,尝试确定高危人群,提高症状性PAD患者中肾动脉狭窄的检出率。方法：回顾性分析105例症状性PAD患者资料,记录动脉血管粥样硬化病变的常见高危因素,结合下肢动脉造影及肾动脉造影结果行单因素及多因素分析,确定变量与症状性PAD合并肾动脉狭窄的关系。结果：症状性PAD合并肾动脉狭窄的患病率为20.00%(21/105)。性别、年龄、吸烟史、糖尿病、高血压、心肌梗死、体质量、身高、体质量指数、白细胞计数、纤维蛋白原定量、血小板计数、平均血小板体积、血脂、钙离子、磷离子、钙磷比、尿酸、血肌酐、PAD临床分型、相似管径的下肢动脉血管病变与ARAS无相关性(P0.05)；eGFrR与RAS有显著相关性(P0.05)。eGFR是RAS患病的独立预测因素。讨论：对于症状性PAD的患者,应在下肢动脉造影术同时行双侧肾动脉造影检查,可以早期发现肾动脉狭窄。
[Abstract]:Objective: to investigate the prevalence and related factors of renal artery stenosis in patients with symptomatic peripheral artery disease (PAD) of lower extremity, and to identify high risk population and to improve the detection rate of renal artery stenosis in patients with symptomatic PAD. Methods: the data of 105 patients with symptomatic PAD were analyzed retrospectively. The common high risk factors of atherosclerosis were recorded. Univariate and multivariate analysis were performed in combination with the results of lower extremity arteriography and renal arteriography. To determine the relationship between variables and symptomatic PAD with renal artery stenosis. Results: the prevalence of symptomatic PAD with renal artery stenosis was 20.00% (21 / 105). Sex, Age, smoking History, Diabetes, Hypertension, Myocardial Infarction, body Mass, height, body Mass Index, WBC count, Fibrinogen Quantification, Platelet count, mean Platelet Volume, Lipid, calcium, phosphorus Ion, The ratio of calcium to phosphorus, uric acid, serum creatinine pad were not correlated with ARAS (P0.05). EGFR was an independent predictor of RAS (P0.05). Discussion: for patients with symptomatic PAD, bilateral renal arteriography should be performed at the same time in lower extremity arteriography to detect early renal artery stenosis.
【学位授予单位】：兰州大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R816.2;R543.5
本文编号：2194509
[Abstract]:Objective: to investigate the prevalence and related factors of renal artery stenosis in patients with symptomatic peripheral artery disease (PAD) of lower extremity, and to identify high risk population and to improve the detection rate of renal artery stenosis in patients with symptomatic PAD. Methods: the data of 105 patients with symptomatic PAD were analyzed retrospectively. The common high risk factors of atherosclerosis were recorded. Univariate and multivariate analysis were performed in combination with the results of lower extremity arteriography and renal arteriography. To determine the relationship between variables and symptomatic PAD with renal artery stenosis. Results: the prevalence of symptomatic PAD with renal artery stenosis was 20.00% (21 / 105). Sex, Age, smoking History, Diabetes, Hypertension, Myocardial Infarction, body Mass, height, body Mass Index, WBC count, Fibrinogen Quantification, Platelet count, mean Platelet Volume, Lipid, calcium, phosphorus Ion, The ratio of calcium to phosphorus, uric acid, serum creatinine pad were not correlated with ARAS (P0.05). EGFR was an independent predictor of RAS (P0.05). Discussion: for patients with symptomatic PAD, bilateral renal arteriography should be performed at the same time in lower extremity arteriography to detect early renal artery stenosis.
【学位授予单位】：兰州大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R816.2;R543.5
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