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原发性肺黏液腺癌的影像学表现

发布时间:2018-11-20 13:10
【摘要】:目的探讨原发性肺黏液腺癌(PPMA)的影像和临床、病理特征及影像诊断价值。方法收集2011年3月—2014年3月宁波大学医学院附属医院经手术病理或穿刺活检证实的7例PPMA患者的临床、影像及病理资料。7例患者均行CT平扫,其中4例行CT多期增强扫描,1例行MR平扫及MR多期增强扫描。观察其影像学表现并与临床和病理结果进行对照。结果 4例单发结节型,1例多发结节型,2例实变型,共9个病灶。外围及胸膜下分布8个,另1个占据整个肺左下叶。最大径0.5~17.3 cm,平均(4.9±5.0)cm。7例病变均未见出血、钙化,分叶、空泡征、血管集束征各4例,空气支气管征、支气管截断征、晕征、胸膜凹陷征各3例,细小短毛刺、棘状突起、碎石路征、卫星播散病灶、血管造影征、肺叶膨隆各2例;3例呈囊实性,实性成分均以边缘分布为主或内部散在斑片样分布;1例MR白肺征,实性成分弥散加权成像(DWI)明显高信号,表观扩散系数(ADC)值明显降低。6例术后病理均为浸润型肺黏液腺癌,分期为Ⅰa期1例,Ⅱa期1例,Ⅲa期4例。1例穿刺活检证实为肺黏液腺癌。结论 PPMA的影像及病理表现有一定的特异性,正确认识其病理学特点,有助于提高对其影像征象的理解和认识。对怀疑肺黏液腺癌的肺实变患者应常规行MR重T2加权像(T2WI)及DWI。
[Abstract]:Objective to investigate the imaging and clinical features, pathological features and diagnostic value of (PPMA) in primary pulmonary mucinous adenocarcinoma. Methods from March 2011 to March 2014, the clinical, imaging and pathological data of 7 patients with PPMA confirmed by surgical pathology or puncture biopsy in affiliated Hospital of Ningbo University Medical College were collected. MR plain scan and MR multiphase enhanced scan were performed in 1 case. Imaging findings were observed and compared with clinical and pathological findings. Results there were 4 cases of single nodular type, 1 case of multiple nodular type and 2 cases of solid type, with 9 lesions. Peripheral and subpleural distribution 8, the other one occupied the entire left lower lobe of the lung. The mean maximum diameter of 0.5 ~ 17.3 cm, was (4.9 卤5.0) cm.7 without bleeding, calcification, lobulation, vacuole sign, vascular cluster sign in 4 cases, air bronchi sign, bronchial truncation sign, halo sign, pleural depression sign in 3 cases, respectively. Small short burr, spinous protuberance, lithotripsy sign, satellite spread lesion, angiographic sign, pulmonary lobus bulge in 2 cases; Saccular solid was found in 3 cases, and the distribution of solid components was mainly marginal distribution or internal speckle-like distribution. In 1 case with white lung sign of MR, (DWI) of solid component diffusion-weighted imaging was obviously high signal, and the (ADC) value of apparent diffusion coefficient was obviously decreased. The pathological features of 6 cases were infiltrating pulmonary mucinous adenocarcinoma, with stage 鈪,

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