周围型肺癌微波消融术后半年CT随访变化

发布时间：2018-11-20 19:53

【摘要】：目的探讨周围型肺癌微波消融术后半年内CT增强随访的恰当次数。方法对24例周围型肺癌微波消融术后患者,采用64层螺旋CT在术后1个月、3个月及6个月行CT增强双期扫描(以3 ml/s的流率注入对比剂),分别在25 s及120 s行胸部扫描。记录病灶治疗前、治疗后、治疗后强化区最大单径之和、治疗后未强化区最大单径之和及治疗后空洞最大内径之和。使用均数间方差检验、配对t检验进行统计学分析。结果病灶最大单径之和在治疗后1个月(3.67±1.16)cm、3个月(3.00±1.00)cm及6个月(2.87±1.13)cm与治疗前病灶最大单径之和(3.42±1.31)cm相比,无显著差异(f=1.025,P=0.391,0.05)。治疗后1个月(0.53±0.53)cm、3个月(0.52±0.55)cm及6个月(0.67±0.81)cm之间,病灶强化区最大单径之和无显著差异(f=0.174,P=0.841,0.05)。治疗后1个月(3.42±1.12)cm、3个月(3.00±0.89)cm及6个月(2.64±0.99)cm之间,病灶未强化区最大单径之和无显著差异(f=1.845,P=0.174,0.05)。治疗后1个月(1.74±1.44)cm、3个月(1.26±1.29)cm及6个月(1.17±1.08)cm之间,病灶空洞最大内径之和无显著差异(f=0.695,P=0.5060.05)。治疗后1个月、3个月及6个月病灶强化区最大单径之和明显小于治疗前病灶最大单径之和(f=16.765,P0.001)。结论周围型肺癌微波消融治疗后病灶大部分发生了坏死,术后半年内CT增强随访未见明显变化,建议术后半年进行一次CT随访。
[Abstract]:Objective to investigate the appropriate times of CT enhancement follow-up in peripheral lung cancer after microwave ablation. Methods Twenty four patients with peripheral lung cancer after microwave ablation were examined with 64-slice spiral CT at 1 month, 3 months and 6 months after operation. CT enhanced dual phase scanning (injection of contrast agent at flow rate of 3 ml/s) was performed on 24 patients with peripheral lung cancer. Chest scans were performed at 25 s and 120 s, respectively. Before and after treatment, the sum of the largest single diameter of the enhanced area, the sum of the largest single path of the unenhanced area and the sum of the maximal cavity inner diameter after treatment were recorded. Statistical analysis was carried out by means of mean variance test and paired t test. Results the sum of the largest single path of the lesion was (3.67 卤1.16) cm, 3 months after treatment and (3.87 卤1.13) cm at 6 months after treatment compared with the sum of the largest single path before treatment (3.42 卤1.31 cm). There was no significant difference (fen 1.025, P < 0.05). 1 month after treatment, there was no significant difference between (0.53 卤0.53) cm, (0.52 卤0.55) cm and (0.67 卤0.81) cm. There was no significant difference between (3.42 卤1.12) cm, 3 months (3.00 卤0.89) cm and 6 months (2.64 卤0.99) cm. 1 month after treatment (1.74 卤1.44) cm, for 3 months (1.26 卤1.29) cm and 6 months for (1.17 卤1.08) cm, there was no significant difference in the sum of the maximum cavity diameter (fen 0.695P 0.5060.05). At 1 month, 3 months and 6 months after treatment, the sum of the maximum single path of the enhanced area was significantly lower than that of the sum of the largest single path of the lesion before treatment (fr 16.765 P0.001). Conclusion most of the lesions have necrosis after microwave ablation of peripheral lung cancer, and the CT enhancement follow-up is not obvious within half a year after operation. It is suggested that the CT follow up should be carried out half a year after operation.
【作者单位】：山东泰安中国人民解放军第八十八医院放射科;第二军医大学附属长征医院影像科;
【分类号】：R734.2;R730.44

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