直肠癌放疗不同技术和体位对小肠受照剂量的影响
发布时间：2018-11-24 13:26
【摘要】：目的探讨不同直肠癌放疗技术对小肠受照剂量的影响。方法选择2015年3月~2018年3月在我院诊断治疗的直肠癌患者31例为研究对象。所有患者照射方案包括俯卧位3D-CRT、仰卧位3D-CRT、俯卧位IMRT与仰卧位IMRT。比较两种治疗体位PTV、小肠、膀胱照射体积,比较相同治疗体位两种照射技术小肠受照体积及相同照射技术不同体位小肠受照体积。结果两组体位靶区PTV与小肠照射体积比较差异无统计学意义(P0.05);俯卧位膀胱照射体积显著小于仰卧位,差异有统计学意义(P0.05)。俯卧位3D-CRT放疗技术小肠V45受照体积显著高于IMRT,差异有统计学意义(P0.05)。仰卧位3D-CRT放疗技术小肠V45受照体积显著高于IMRT,差异有统计学意义(P0.05)。3D-CRT技术下仰卧位小肠V45显著高于俯卧位,差异有统计学意义(P0.05)。IMRT放疗技术下仰卧位小肠V45显著高于俯卧位,差异有统计学意义(P0.05)。结论相同的体位,IMRT相对于3DCRT小肠照射剂量更少,而相同的照射技术下,俯卧位小肠V45更小,提示俯卧位照射能够减少小肠的受照剂量。
[Abstract]:Objective to investigate the effects of different radiotherapy techniques on small intestine irradiation dose in rectal cancer. Methods 31 patients with rectal cancer diagnosed and treated in our hospital from March 2015 to March 2018 were selected. All patients were treated with 3D-CRT in prone position, 3D-CRT in supine position, IMRT in prone position and IMRT. in supine position. The small intestine irradiation volume and bladder irradiation volume of PTV, were compared between the two treatment positions, the small intestinal irradiation volume with the same therapeutic posture and the small intestinal irradiation volume with the same irradiation technique. Results there was no significant difference in body position target area PTV and small intestine irradiation volume between the two groups (P0.05), and the volume of bladder irradiation in prone position was significantly smaller than that in supine position (P0.05). The radiation volume of V 45 was significantly higher than that of IMRT, in prone position 3D-CRT radiotherapy (P0.05). The irradiation volume of small intestine V45 in supine 3D-CRT was significantly higher than that in IMRT, (P0.05). In supine position, V45 was significantly higher in supine position than in prone position (P0.05), while in supine position V45 was significantly higher than that in prone position (P0.05). The difference was statistically significant (P0.05). The small intestine V45 in supine position was significantly higher than that in prone position under). IMRT radiotherapy (P0.05). Conclusion under the same posture, the dose of IMRT is lower than that of 3DCRT, and the V45 of prone position is smaller than that of 3DCRT, which suggests that the irradiation in prone position can reduce the dose of small intestine irradiation.
【作者单位】： 浙江省肿瘤医院放射物理室
【基金】：浙江省医药卫生一般研究计划(B类)(2015KYB070)
【分类号】：R735.37
[Abstract]:Objective to investigate the effects of different radiotherapy techniques on small intestine irradiation dose in rectal cancer. Methods 31 patients with rectal cancer diagnosed and treated in our hospital from March 2015 to March 2018 were selected. All patients were treated with 3D-CRT in prone position, 3D-CRT in supine position, IMRT in prone position and IMRT. in supine position. The small intestine irradiation volume and bladder irradiation volume of PTV, were compared between the two treatment positions, the small intestinal irradiation volume with the same therapeutic posture and the small intestinal irradiation volume with the same irradiation technique. Results there was no significant difference in body position target area PTV and small intestine irradiation volume between the two groups (P0.05), and the volume of bladder irradiation in prone position was significantly smaller than that in supine position (P0.05). The radiation volume of V 45 was significantly higher than that of IMRT, in prone position 3D-CRT radiotherapy (P0.05). The irradiation volume of small intestine V45 in supine 3D-CRT was significantly higher than that in IMRT, (P0.05). In supine position, V45 was significantly higher in supine position than in prone position (P0.05), while in supine position V45 was significantly higher than that in prone position (P0.05). The difference was statistically significant (P0.05). The small intestine V45 in supine position was significantly higher than that in prone position under). IMRT radiotherapy (P0.05). Conclusion under the same posture, the dose of IMRT is lower than that of 3DCRT, and the V45 of prone position is smaller than that of 3DCRT, which suggests that the irradiation in prone position can reduce the dose of small intestine irradiation.
【作者单位】： 浙江省肿瘤医院放射物理室
【基金】：浙江省医药卫生一般研究计划(B类)(2015KYB070)
【分类号】：R735.37
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