正常成人多层螺旋CT灌注成像的头皮皮瓣脑血流动力学研究

发布时间：2018-11-25 19:13

【摘要】：目的:探讨多层螺旋CT灌注成像(MSCTPI)技术在正常人头皮皮瓣脑血流动力学中的应用。方法:选取近5年因其他原因行全脑灌注及CTA检查正常患者60例,获得的数据通过体部灌注软件进行分析,分别测定额部、颞部、枕部头皮皮瓣的血流量、血容量、达峰时间,并对其进行定量分析。结果:MSCTPI显示正常成人头皮皮瓣的平均血流量(TBF)额、颞、枕分别为(47.61±7.06)mL/(min·100g)、(45.52±6.52)mL/(min·100g)、(41.84±6.22)mL/(min·100g);平均血容量(TBV)额、颞、枕分别为(40.43±6.00)mL/100g、(30.13±4.72)mL/100g、(31.89±5.50)mL/100g;达峰时间(TTP)额、颞、枕分别为(25.00±4.02)s、(27.50±4.52)s、(28.00±5.03)s。分别对额部与颞部、额部与枕部的头皮灌注数值TBF、TBV、TTP做两独立样本T检验,P均0.05,额部的血供较丰富。结论:MSCTPI技术为测量正常成人头皮血流动力学提供了一种新的方法,为评估头皮血供的异常界定了一个标尺。为进一步解决大面积颅骨修补术后钛网外露奠定了基础。
[Abstract]:Objective: to investigate the application of multislice spiral CT perfusion (MSCTPI) in cerebral hemodynamics of scalp flap in normal subjects. Methods: 60 patients with normal brain perfusion and CTA examination were selected for other reasons in recent 5 years. The data were analyzed by body perfusion software. The blood flow, blood volume and peak time of frontal, temporal and occipital scalp flaps were measured respectively. The quantitative analysis was carried out. Results: MSCTPI showed that the mean blood flow of the scalp flap was (47.61 卤7.06) mL/ (min 100g), (45.52 卤6.52) mL/ (min 100g), (41.84 卤6.22) mL/ (min 100g). The mean blood volume of (TBV), temporal and occipital were (40.43 卤6.00) mL/100g, (30.13 卤4.72) mL/100g, (31.89 卤5.50) mL/100g;, respectively. The peak time of (TTP), temporal and occipital were (25.00 卤4.02) s, (27.50 卤4.52) s, (28.00 卤5.03) s. Two independent T tests were performed on the scalp perfusion values of frontal and temporal, frontal and occipital regions, respectively (P < 0.05). Conclusion: MSCTPI provides a new method for measuring hemodynamics of scalp in normal adults and defines a scale for evaluating the abnormal blood supply of scalp. It lays a foundation for solving the exposure of titanium mesh after large-area skull repair.
【作者单位】：昆明医科大学第二附属医院;
【基金】：云南省应用基础研究计划面上项目(2013FB048)
【分类号】：R816.1

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