Beta频段双耳差频声刺激对大脑生理状态的影响

发布时间：2018-12-14 20:11

【摘要】：随着载人航天事业的快速发展,航天员的大脑状态调控以及警觉度提高技术成为航天人因工程研究热点和难点问题之一。为了探究beta段差频声刺激对大脑状态的调控作用,在Nback任务过程中进行了beta段双耳差频声刺激组和对照组平行实验。根据实验中的N-back反应时和正确率分类,划分成三组对beta频段差频声刺激敏感程度不同的受试人群,分别是敏感组、中间组和非敏感组,分析beta频段功率谱密度差值、(alpha+theta)/beta的比值、非线性特征样本熵和互信息脑网络等特征。结果表明,双耳差频声刺激的脑区激活存在个体差异性,对声刺激敏感的受试者,差频刺激下,脑电功率谱中的beta频段在右颞区能量增强(T4,p0.005),T3电极处三组人群(alpha+theta)/beta比值具有显著差异性,敏感人群中刺激组样本熵值比对照组高10.53%,且互信息集群系数最高(0.971),脑网络信息交流增强,这说明差频声刺激能改变大脑的生理状态,在提高航天员的注意力和警觉度、对抗脑力疲劳方面具有应用前景。
[Abstract]:With the rapid development of manned spaceflight, the technology of brain state regulation and alertness improvement of astronauts has become one of the hot and difficult problems in spaceflight human engineering. In order to investigate the effect of beta segment differential frequency sound stimulation on brain state, parallel experiments were carried out in the beta segment binaural differential frequency sound stimulation group and the control group during the Nback task. According to the classification of N-back reaction time and correct rate in the experiment, three groups of subjects with different sensitivity to beta frequency difference were divided into three groups, namely, sensitive group, middle group and non-sensitive group. The difference of power spectral density in beta band was analyzed. The ratio of (alpha theta) / beta, nonlinear feature sample entropy and mutual information brain network. The results showed that there were individual differences in the activation of brain regions in the two ear differentially stimulated subjects. In subjects sensitive to acoustic stimulation, the beta band in the EEG power spectrum was enhanced in the right temporal region (T4, p0.005). The ratio of (alpha theta) / beta was significantly different among the three groups at the T3 electrode. The entropy value of the stimulation group was 10.53 higher than that of the control group, and the mutual information cluster coefficient was the highest (0.971), and the information exchange of brain network was enhanced. This indicates that the differential frequency acoustic stimulation can change the physiological state of the brain and has the application prospect in improving the attention and alertness of the astronauts and fighting mental fatigue.
【作者单位】：天津大学精密仪器与光电子工程学院;中国航天员科研训练中心人因工程重点实验室;天津市生物医学检测技术与仪器重点实验室;
【基金】：国家自然科学基金项目(No.51377120;51007063;31271062;81222021;61172008;81171423) 天津市自然基金项目(No.13JCQNJC13900) 国家科技支撑计划项目(No.2012BAI34B02) 教育部新世纪优秀人才支持计划项目(No.NCET-10-0618)
【分类号】：R85

【相似文献】