力量训练对增龄性血管内皮功能的影响及机制

发布时间：2018-12-16 18:33

【摘要】：目的:研究力量训练对老年人血管内皮功能和炎症因子的影响,探讨力量训练对增龄性血管内皮功能影响的机制。方法:11例老年男性[平均年龄(70.63±3.93)岁]进行12周的力量训练,使用多普勒超声显像技术测定受试者运动训练前后的血流介导的内皮依赖性血管舒张功能(FMD),同时检测血清肿瘤坏死因子-α(TNF-α)、白细胞介素6(IL-6)、超敏C反应蛋白(hs CRP)、脂联素(adiponectin)。结果:经过12周的力量训练后,老年人体脂率显著降低(P0.05),血糖、血脂出现显著性下降,肌肉力量显著增加,同时FMD显著提高(P0.05),而TNF-α、IL-6、hs CRP水平出现显著降低,adiponectin显著升高;FMD增加的程度与血清TNF-α、IL-6、hs CRP降低的程度,以及adiponectin升高的程度呈显著正相关。结论:12周的力量训练提高了老年人血管内皮功能,减低了炎症反应水平;力量训练提高老年人血管内皮功能与炎症水平下降有关,这可能是力量训练提高老年人心血管机能的机制之一。
[Abstract]:Aim: to study the effects of strength training on vascular endothelial function and inflammatory factors in the elderly and to explore the mechanism of strength training on aging vascular endothelial function. Methods: eleven elderly men [mean age (70.63 卤3.93) years] were trained for 12 weeks. Doppler ultrasound was used to measure the flow mediated endothelium-dependent vasodilation function (FMD),) before and after exercise training. Serum tumor necrosis factor- 伪 (TNF- 伪), interleukin-6 (IL-6) and hyper-sensitive C-reactive protein (hs CRP), adiponectin (adiponectin). Were also detected. Results: after 12 weeks of strength training, the body fat rate of the elderly significantly decreased (P0.05), blood glucose and blood lipid decreased significantly, muscle strength increased significantly, and FMD increased significantly (P0.05), while TNF- 伪, IL-6, increased significantly (P0.05). The level of hs CRP decreased significantly and adiponectin increased significantly. The increase of FMD was positively correlated with the decrease of serum TNF- 伪, IL-6,hs CRP and the increase of adiponectin. Conclusion: after 12 weeks of strength training, the vascular endothelial function of the elderly was improved, and the level of inflammation was decreased. The improvement of vascular endothelial function in the elderly by strength training is related to the decrease of inflammation, which may be one of the mechanisms of strength training to improve cardiovascular function in the elderly.
【作者单位】：石家庄学院体育学院运动人体科学实验中心;
【基金】：石家庄学院科研平台启动基金项目(xJp T005)
【分类号】：R87

【共引文献】