Revolution CT全胃灌注扫描时间间隔对正常胃壁灌注数据的影响

发布时间：2019-02-13 12:57

【摘要】：目的:探讨Revolution CT全胃灌注扫描时间间隔对正常胃壁灌注数据的影响。方法:前瞻性分析于我院行Revolution CT腹部灌注且无胃部疾病患者28例,按临床申请范围不同分为连续灌注组(A组)14例,间隔灌注组(B组)14例。两组灌注扫描均为轴扫模式,Z轴覆盖范围均为160 mm,A组连续采集25次,每次采集时间为2 s(曝光0.5 s,间隔1.5 s),总扫描时间50 s。B组在第15 s即采集8次后进行全腹动脉期螺旋扫描,螺旋扫描模式与轴扫模式互相转换及扫描曝光时间12~16.2 s,再进行13次上腹轴位灌注扫描,共采集21次,总扫描时间50~54.2 s。所有图像经运动校正后传至工作站进行灌注成像分析。两名观察者分别测量胃体部大、小弯侧感兴趣区的灌注参数值,包括BV、BF、MTT、TP、PEI、MSI、IRF、Tmax,统计各组灌注辐射剂量。使用组内相关系数(ICC)对所得数据进行一致性检验,采用配对样本t检验及独立样本t检验比较两组内及组间各灌注参数的差异。结果:两观察者数据测量一致性较好。两组内胃大弯侧BV值((12.83±4.30)、(18.44±4.39)m L/(min·100 g))、BF值((61.54±10.13)、(64.99±13.77)m L/100 g)均高于小弯侧BV值((9.73±3.87)、(14.28±5.40)m L/(min·100 g))、BF值((47.77±12.29)、(47.09±10.52)m L/100 g),P值分别为0.027、0.004、0.002、0.000,其余灌注参数值(MTT、TP、MSI、PEI、IRF、Tmax)差异无统计学意义;两组间BV、PEI值在胃大、小弯侧差异均有统计学意义(P=0.002、0.004、0.017、0.032),MTT及Tmax值仅在小弯侧差异有统计学意义,在大弯侧差异无统计学意义,且A组均低于B组,余灌注参数值(BF、TP、MSI、IRF)两组间差异无统计学意义。A组剂量为14.46 m Sv,B组为12.15 m Sv,B组较A组降低15.97%。结论:Revolution CT全胃灌注扫描时间间隔对正常胃壁BV、MTT、PEI及Tmax等灌注参数有影响,但对BF、TP、MSI、IRF值无影响,且胃大、小弯侧BV、BF灌注值不同。
[Abstract]:Objective: to investigate the effect of Revolution CT total gastric perfusion time interval on normal gastric wall perfusion data. Methods: 28 patients with Revolution CT abdominal perfusion without gastric diseases were prospectively analyzed. According to the clinical application range, 14 patients were divided into continuous perfusion group (group A) and septal perfusion group (group B). Two groups of perfusion scan were axial scan mode, Z axis coverage was 160 mm,A group 25 consecutive acquisition, each acquisition time was 2 s (exposure 0.5 s, interval 1.5 s),) The total scanning time was 50 s. B group underwent total abdominal arterial spiral scanning at 15 s, that is, 8 times. The spiral scan mode and axial scan mode were converted to each other and the exposure time was 12 ~ 16.2 s, and 13 axial perfusion scans were performed. A total of 21 times were collected, and the total scanning time was 50 ~ 54.2 s. All images were transmitted to workstation after motion correction for perfusion imaging analysis. The perfusion parameters of the large and small curved side of stomach were measured by two observers, including BV,BF,MTT,TP,PEI,MSI,IRF,Tmax,. Correlation coefficient (ICC) was used to test the consistency of the data. The difference of perfusion parameters between the two groups was compared by paired sample t test and independent sample t test. Results: the data of two observers were consistent. The BV value of the great curvature side of the stomach (12.83 卤4.30), (18.44 卤4.39) mL / (min 100 g), BF) (61.54 卤10.13), (64.99 卤13.77 mL / 100g) was higher than that of the small flexural side (9.73 卤3.87). The values of (14.28 卤5.40) mL / (min 100 g), BF) (47.77 卤12.29), (47.09 卤10.52) mL / 100 g), P were 0.027 卤5.40 mL / (MTT,TP,MSI,PEI,IRF, = 0.002 卤0.000), respectively. There was no significant difference in Tmax. There were significant differences in BV,PEI between the two groups in the large stomach and small curvature (P0. 002, 0. 004, 0. 017, 0. 032), MTT and Tmax, respectively. There was no significant difference between the two groups in the great curvature, and the difference in group A was lower than that in group B. There was no significant difference in residual perfusion parameter (BF,TP,MSI,IRF) between the two groups, but the dose of 14.46m Sv,B in group A was 12.15m Sv,B lower than that in group A (15.97m). Conclusion the interval of: Revolution CT total gastric perfusion scan has influence on BV,MTT,PEI and Tmax of normal gastric wall, but it has no effect on BF,TP,MSI,IRF value, and the BV,BF perfusion value of large and small curvature of stomach is different.
【作者单位】：大连医科大学附属第一医院放射科;
【分类号】：R816.5

【参考文献】