灌注成像与CT增强扫描对脑胶质瘤术前分级的判断准确性观察

发布时间：2019-03-26 14:51

【摘要】：目的观察并分析灌注成像与CT增强扫描对脑胶质瘤术前分级的判断准确性。方法对2009年1月至2012年12月来我院就诊并治疗的76例脑胶质瘤患者作回顾性分析,进行灌注扫描与CT增强扫描,以两种诊断方法的影像学资料为基础,灌注成像参考脑血容量(CBV)、脑血流量(CBF)和脑血管表面通透性(PS)和相对脑血容量(r CBV)值进行术前分级,CT增强扫描以影像学图片为判断依据,对比术后病理结果,比较两组术前分级准确率。结果以术后病理结果为标准,灌注成像中,两级别组病灶区域的CBF、PS、CBV、r CBV值均大于对侧正常区域的对应值(P0.05),高级别组各灌注参数显著大于低级别组对应值(P0.05)。灌注成像在低级别组、高级别组的判断准确率分别为90.24%、91.43%,均显著高于CT增强扫描的准确率73.17%、71.43%(P0.05)。结论灌注成像对脑胶质瘤术前分级准确性均高于CT增强扫描,是一种有效的胶质瘤术前诊断技术。
[Abstract]:Objective to observe and analyze the accuracy of perfusion imaging and CT enhanced scan in preoperative grading of brain gliomas. Methods from January 2009 to December 2012, 76 patients with glioma were analyzed retrospectively. Perfusion scan and CT enhanced scan were performed, based on the imaging data of two diagnostic methods. Cerebral blood volume (CBV), cerebral blood flow (CBF), cerebral vascular permeability (PS) (PS) and relative cerebral blood volume (r CBV) were used for preoperative grading by perfusion imaging. CT enhancement scan was based on imaging images. The postoperative pathological results were compared and the preoperative grading accuracy was compared between the two groups. Results according to the postoperative pathological results, the CBF,PS,CBV,r CBV value in the lesion region of the two-stage group was higher than that of the contralateral normal area in perfusion imaging (P0.05). The perfusion parameters in the high-level group were significantly higher than those in the low-level group (P0.05). The accuracy of perfusion imaging in low-grade group and high-level group was 90.24% and 91.43% respectively, which was significantly higher than that of CT-enhanced scanning (73.17%, 71.43%) (P0.05). Conclusion the preoperative grading accuracy of perfusion imaging is higher than that of CT enhanced imaging. It is an effective technique for preoperative diagnosis of glioma. [WT5 "HZ] [WT5" HZ] conclusion [WT5 "BZ]
【作者单位】：湖北省荆州市第一人民医院神经外科;湖北省荆州市第一人民医院放射科;
【分类号】：R739.41;R730.44

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