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40岁以上女性身体成分与血流介导的血管内皮舒张功能的研究

发布时间:2019-05-22 00:57
【摘要】:研究目的:通过研究40岁以上女性身体成分和作为心血管早期的独立预测因子FMD的变化及二者之间的关系,为女性早期预防肥胖、骨质疏松和心血管疾病提供理论依据,为指导中老年女性科学健身提供实证支持。 研究方法:受试者是来自北京市海淀区的156名40岁以上的女性,通过问卷获取基本资料以及体力活动水平,通过实验室形态测试获取身高、体重和三围指标、通过双能量X线吸收法(DEXA)获取骨密度和体成分各指标、以及通过超声检测获取FMD、基础(最大)直径、血流速度及时间等。问卷数据用e pidata录入,数据分析使用SPSS16.0. 研究结果:40岁以上女性,随着年龄的增长:(1)全身及各个部位的骨密度都有所下降,下降幅度与部位有关,与40-44岁组相比,60岁以上组脊柱部位降幅最大(△=0.145g/cm2;p0.01);(2)全身骨矿物质含量及瘦软组织含量均明显的下降,与40-44岁组相比,60岁以上组降幅分别为(△=374.1g,△=1600g;p0.05);(3)与40-44岁组相比,60岁以上组肱动脉FMD出现了增龄性的下降,降幅为0.74%,但无显著性差异。基础直径、安静血流速度以及最大血流速度等出现了增龄性的增大;(4)FMD与身体成分之间相关性不明显,但是基础直径和最大直径与身体成分有相关性,特别是与全身瘦软组织含量呈负相关(r=-0.4和r=-0.39:p0.01);(5)较高的体力活动水平对瘦软组织含量的影响最大,与体力活动缺乏组相比,体力活动水平较高组增幅为4.1kg。 结论:(1)年龄增长是引起40岁以上女性身体形态和血管功能发生变化的一个重要因素。对人体健康有着举足轻重的作用。(2)40岁以上女性,瘦软组织含量和基础直径的关系提示瘦软组织含量的丢失对心血管事件的危害可能比脂肪堆积更为严重。(3)体力活动对血管功能的积极影响可能是通过改变身体各成分的含量而发挥其作用的。
[Abstract]:Objective: to study the changes of body composition and independent predictors FMD as early cardiovascular predictors in women over 40 years of age and the relationship between them, so as to provide theoretical basis for early prevention of obesity, osteoporosis and cardiovascular disease in women. In order to guide middle-aged and elderly women to provide empirical support for scientific fitness. Methods: the subjects were 156 women over 40 years old from Haidian District of Beijing. The basic data and physical activity level were obtained by questionnaire, and the height, weight and BWH indexes were obtained by laboratory morphology test. Bone mineral density (bone mineral density) and body composition were obtained by dual energy X-ray absorptiometry (DEXA), and basic (maximum) diameter, blood flow velocity and time of FMD, were obtained by ultrasound. The questionnaire data is input by e pidata, and the data analysis is analyzed by SPSS16.0.. The results showed that the bone mineral density of women over 40 years old decreased with the increase of age: (1) the bone mineral density of the whole body and all parts decreased, and the extent of decrease was related to the location, compared with the group of 40 years old and 44 years old. The decrease of spinal position was the largest in the group over 60 years old (= 0.145g / cm ~ 2). P0.01); (2) the bone mineral content and the content of thin soft tissue in the whole body decreased significantly, which were significantly lower than those in the group over 60 years old (= 374.1 g, = 1600 g / p0.05), compared with those in the group aged 40 脳 44 years old, and the content of bone mineral and soft tissue in the group over 60 years old was significantly lower than that in the group over 44 years old. (3) compared with 40 鈮,

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