128层螺旋CT低剂量扫描检查孤立性肺内结节性病灶的研究

发布时间：2019-05-29 19:47

【摘要】：目的:探讨多排螺旋CT(128排)低剂量扫描参数下检查孤立性肺内结节的可行性研究。方法:随机连续搜集我院低剂量(30m A)CT肺体检者,发现肺内结节病灶患者13例,对其进一步以常规剂量(350m A)CT精细扫描,比较低剂量扫描及常规剂量扫描肺结节大小差异。结果:两种剂量扫描策略均检查出46枚结节。常规剂量与低剂量测得各部位结节体积分别为:肺尖部:(431.3±92.8)mm~3,(658.4±94.4)mm~3,肺中部:(3025.8±526.7)mm~3,(2989.4±520.4)mm~3,肺底部:(1241.5±438.9)mm~3,(1266.0±447.6)mm~3,肺尖部肺结节大小差异明显,肺中部及肺底部肺结节大小均无显著性差异(P0.05)。常规剂量与低剂量测得结节体积(除外肺尖部位结节5枚)分别为,组1:(39.8±14.6)mm~3,(40.7±15.5)mm~3;组2:(202±106.3)mm~3,(204.1±103.6)mm~3;组3:(4179.7±4410.4)mm~3,(4190.5±4487.2)mm~3。三组组内测量结果均无显著性差异(P0.05)。常规剂量与低剂量测得非实性结节密度[(-68.3±24.2)HU,(-64.6±22.8)HU]及实性结节结节密度[(97.5±69.5)HU,(107.2±90)HU]均无统计学差异(P0.05)。结论:低剂量更加有利于肺内孤立结节患者扫描复查病灶,可以应用推广。
[Abstract]:Objective: to investigate the feasibility of detecting solitary pulmonary nodules under low dose scanning parameters of multi-slice spiral CT. Methods: 13 patients with pulmonary nodular lesions were randomly collected in our hospital with low dose (30m A) CT). The patients were further scanned with conventional dose (350m A) CT). The size of pulmonary nodules was compared between low dose scanning and conventional dose scanning. Results: 46 nodules were detected by both dose scanning strategies. The volume of nodules measured by conventional dose and low dose was (431.3 卤92.8) mm~3, (658.4 卤94.4) mm~3, and (3025.8 卤526.7) mm~3, (2989.4 卤520.4) mm~3, respectively. There was significant difference in the size of pulmonary nodules in the apex of the lung: (1241.5 卤438.9) mm~3, (1266.0 卤447.6) mm~3, but there was no significant difference in the size of the pulmonary nodules in the middle and bottom of the lung (P 0.05). The volume of nodules measured by conventional dose and low dose (except 5 nodules at apical part of lung) was (39.8 卤14.6) mm~3, (40.7 卤15.5) mm~3;, 2: (202 卤106.3) mm~3, (204.1 卤103.6) mm~3;, respectively. Group 3: (4179.7 卤4410.4) mm~3, (4190.5 卤4487.2) mm~3. There was no significant difference in the measurement results among the three groups (P 0.05). There was no significant difference in the density of non-solid nodules [(- 68.3 卤24.2) HU, (- 64.6 卤22.8) HU] and the density of solid nodules [(97.5 卤69.5) HU, (107.2 卤90) HU] between conventional and low doses (P 0.05). Conclusion: low dose is more beneficial to scan and reexamine the lesions in patients with solitary pulmonary nodules, which can be applied and popularized.
【作者单位】：辽宁省人民医院放射科;
【基金】：辽宁省卫生计生委基金项目(LNCCC-D34-2015)
【分类号】：R563;R816.41

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