儿童青少年游泳运动员初入2366米高原肺动脉收缩压及心脏功能变化的超声心动图研究
发布时间：2019-06-11 15:19
【摘要】：目的:采用彩色多普勒超声心动图估测初入高原儿童青少年游泳运动员肺动脉收缩压并测量心脏功能参数,探讨高原低氧暴露对儿童青少年游泳运动员肺动脉压及心脏功能的影响。方法:以儿童青少年游泳运动员共33人为研究对象,平均年龄12.25±0.36岁。分别于高原前以及进入高原(海拔2366米)12小时采用彩色多普勒超声心动图估测肺动脉收缩压并测量心脏功能参数。彩超检查日晨起,肘正中静脉取血,测试血清内皮素(ET-1)和一氧化氮(NO)。于进入高原12小时进行急性高山病(AMS)评分并完成高原肺水肿(HAPE)早期症状问诊。结果:(1)33名运动员均未出现HAPE的相应症状;(2)初入高原儿童青少年游泳运动员肺动脉收缩压(PASP)显著高于高原前水平(20.32±3.71 vs 18.14±3.69 mm Hg,P0.05)且与年龄呈负相关(r=-0.26,P0.01),其最高值为29 mm Hg;(3)初入高原儿童青少年游泳运动员SV下降,心率升高而CO升高。左心室Tei指数以及右心室Tei指数均未发生显著变化(0.34±0.09 vs 0.32±0.06,P0.05;0.28±0.04 vs0.24±0.09,P0.05);(4)初入高原儿童青少年游泳运动员血清ET-1显著高于高原前水平(123.45±23.45 vs109.57±15.32 ng/l,P0.05),且与PASP正相关(r=0.3,P=0.035)。血清NO显著低于高原前水平(120.78±32.55 vs 136.42±36.97μmol/l,P0.05),且与PASP负相关(r=-0.306,P=0.042)。结论:(1)海拔2366米高原可以引起儿童青少年游泳运动员PASP升高,PASP升高与ET-1的释放增加以及NO合成减少有关,而PASP升高并未对心脏功能构成影响;(2)海拔2366米高原儿童青少年游泳运动员AMS以及HAPE的发生率较低。
[Abstract]:Objective: to evaluate pulmonary artery systolic pressure and cardiac function parameters of newly entered juvenile swimmers by color Doppler echocardiography, and to explore the effect of hypoxia exposure at high altitude on pulmonary artery pressure and cardiac function of child and adolescent swimmers. Methods: a total of 33 young swimmers with an average age of 12.25 卤0.36 years were studied. Pulmonary artery systolic pressure and cardiac function parameters were estimated by color Doppler echocardiography before plateau and 12 hours after entering altitude (2366 meters above sea level). Blood samples were taken from the median cubital vein from the morning after color Doppler ultrasound examination, and serum endothelin (ET-1) and nitric oxide (NO). Were measured. The (AMS) score of acute high mountain disease and the early symptoms of (HAPE) in high altitude pulmonary edema were evaluated at 12 hours after entering the plateau. Results: (1) there was no corresponding symptom of HAPE in 33 athletes, and (2) the pulmonary artery systolic blood pressure (PASP) of newly entered high altitude children and adolescents was significantly higher than that of pre-altitude level (20.32 卤3.71 vs 18.14 卤3.69 mm Hg,P0.05) and negatively correlated with age (r 鈮，
本文编号：2497291
[Abstract]:Objective: to evaluate pulmonary artery systolic pressure and cardiac function parameters of newly entered juvenile swimmers by color Doppler echocardiography, and to explore the effect of hypoxia exposure at high altitude on pulmonary artery pressure and cardiac function of child and adolescent swimmers. Methods: a total of 33 young swimmers with an average age of 12.25 卤0.36 years were studied. Pulmonary artery systolic pressure and cardiac function parameters were estimated by color Doppler echocardiography before plateau and 12 hours after entering altitude (2366 meters above sea level). Blood samples were taken from the median cubital vein from the morning after color Doppler ultrasound examination, and serum endothelin (ET-1) and nitric oxide (NO). Were measured. The (AMS) score of acute high mountain disease and the early symptoms of (HAPE) in high altitude pulmonary edema were evaluated at 12 hours after entering the plateau. Results: (1) there was no corresponding symptom of HAPE in 33 athletes, and (2) the pulmonary artery systolic blood pressure (PASP) of newly entered high altitude children and adolescents was significantly higher than that of pre-altitude level (20.32 卤3.71 vs 18.14 卤3.69 mm Hg,P0.05) and negatively correlated with age (r 鈮，
本文编号：2497291
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