马拉松膝关节软骨MR定量研究及软骨自动分割软件的临床效能评估
发布时间：2021-11-11 09:56
随着生活水平和健康观念的提升,长跑已经成为一种流行的娱乐活动,我国马拉松赛事的举办逐年增加。据统计,2017年全国各地共举办马拉松及相关运动赛事1100场,在2011-2017年间,赛事场次增加了五十多倍。由于缺乏专业的跑步知识和系统的指导,跑步者在跑步过程中很容易出现损伤,其中膝关节的损伤概率最高。马拉松影像研究在国外数量不多,在国内几乎空白。本研究通过T2 mapping成像观察马拉松前后膝关节软骨T2值的变化,评价跑者在马拉松后是否会出现膝关节软骨的损伤。在常规的MR图像中,我们仅能得到一些二维信息,并且测量定量的数值如T2、T2*值要进行每个层面的手动勾画,而三维重建图像克服了常规二维图像的不足,本研究利用膝关节软骨自动分割软件（Siemens Chondral Health,Version 2.1,Siemens Healthcare,Erlangen,Germany）获得软骨T2*值及软骨体积值,进行手动校正后,验证该软件的临床应用价值。第一部分应用T2 mapping成像评价马拉松前后膝关节软骨短中期改变目的:应用T2 mapping成像评价非专业长跑者马拉松前后膝关节软...
【文章来源】：河北医科大学河北省
【文章页数】：55 页
【学位级别】：硕士
【部分图文】：
正常膝关节软骨MRI图像
19图2正常膝关节软骨MRI图像Fig.2MRIimagingofnormalkneecartilageDuringthepre-competition(a),post-competition(b)and2monthsafterthecompetition(c),therewasnoobviousabnormalsignalinthekneecartilage.Thecartilagewasintactwithsmoothsurface.Theshapeandsignalofthemeniscus,ligamentsandtendonswerenormal.Therewasnoeffusionandcorpusliberuminarticularcapsule.图3骨髓水肿MRI图像Fig.3MRIimagingofbonemarrowedemaOnevolunteerhadbonemarrowedemainthedistalfemurandproximaltibiabeforetherace(a).Aftertherace,therangeofedemawasslightlyreducedandthesignalintensitywasweakened(b).Bonemarrowedemawaslargelydisappearedafter2monthsoffollow-up(c).2．关节软骨T2值改变关节软骨浅层T2值在赛前、赛后12h内及2个月随访时均高于深层（t值分别为11.095、10.385、10.102，P值均<0.01），差异有统计学意义。与赛前相比，赛后12h内关节软骨浅层T2值降低，差异有统计学意义；赛后2个月随访时，差异无统计学意义（见表2）。而深层区域整体软骨T2值在赛后12h内及赛后2个月随访时与赛前相比，差异均无统计学意义（见abcabc
378,0.028*1.488,0.153,147,0.005*0.467,0.645-0.594,0.5600.559,0.581-1.135,0.2710.849,0.405-0.812,0.4270.797,0.434-0.519,0.607Note:T2（ms）valuesarepresentedasmean±standarddeviation.*Significantdifference(P<0.05)SZ:superficialzoneofkneecartilage,DZ:deepzoneofkneecartilage,MTP:medialtibialplateau,LTP:lateraltibialplateau,MFC:medialfemoralcondyle,LFC:lateralfemoralcondyle,1:pre-competition,2:within12hafterthecompetition,3:twomonthsafterthecompetition.图4三次扫描膝关节浅层软骨T2值变化趋势图Fig.4TendencychartofT2valueinsuperficialcartilageofkneeFromtheresultsofthreescans,wecanseethatT2valueofthemostsuperficialcartilageofkneejointshowedatendencyof"descendingfirstandthenrising",however,theT2valueintheLFCandMFCcartilagesubregion
本文编号：3488653
【文章来源】：河北医科大学河北省
【文章页数】：55 页
【学位级别】：硕士
【部分图文】：
正常膝关节软骨MRI图像
19图2正常膝关节软骨MRI图像Fig.2MRIimagingofnormalkneecartilageDuringthepre-competition(a),post-competition(b)and2monthsafterthecompetition(c),therewasnoobviousabnormalsignalinthekneecartilage.Thecartilagewasintactwithsmoothsurface.Theshapeandsignalofthemeniscus,ligamentsandtendonswerenormal.Therewasnoeffusionandcorpusliberuminarticularcapsule.图3骨髓水肿MRI图像Fig.3MRIimagingofbonemarrowedemaOnevolunteerhadbonemarrowedemainthedistalfemurandproximaltibiabeforetherace(a).Aftertherace,therangeofedemawasslightlyreducedandthesignalintensitywasweakened(b).Bonemarrowedemawaslargelydisappearedafter2monthsoffollow-up(c).2．关节软骨T2值改变关节软骨浅层T2值在赛前、赛后12h内及2个月随访时均高于深层（t值分别为11.095、10.385、10.102，P值均<0.01），差异有统计学意义。与赛前相比，赛后12h内关节软骨浅层T2值降低，差异有统计学意义；赛后2个月随访时，差异无统计学意义（见表2）。而深层区域整体软骨T2值在赛后12h内及赛后2个月随访时与赛前相比，差异均无统计学意义（见abcabc
378,0.028*1.488,0.153,147,0.005*0.467,0.645-0.594,0.5600.559,0.581-1.135,0.2710.849,0.405-0.812,0.4270.797,0.434-0.519,0.607Note:T2（ms）valuesarepresentedasmean±standarddeviation.*Significantdifference(P<0.05)SZ:superficialzoneofkneecartilage,DZ:deepzoneofkneecartilage,MTP:medialtibialplateau,LTP:lateraltibialplateau,MFC:medialfemoralcondyle,LFC:lateralfemoralcondyle,1:pre-competition,2:within12hafterthecompetition,3:twomonthsafterthecompetition.图4三次扫描膝关节浅层软骨T2值变化趋势图Fig.4TendencychartofT2valueinsuperficialcartilageofkneeFromtheresultsofthreescans,wecanseethatT2valueofthemostsuperficialcartilageofkneejointshowedatendencyof"descendingfirstandthenrising",however,theT2valueintheLFCandMFCcartilagesubregion
本文编号：3488653
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