封闭负压引流对猪肢体枪弹软组织贯通伤初期治疗实验研究

发布时间：2018-02-25 17:36

本文关键词： 枪弹伤封闭负压引流动物研究　出处：《实用医学杂志》2010年09期 　论文类型：期刊论文

【摘要】：目的:观察封闭负压引流(VSD)对猪肢体枪弹软组织贯通伤初期治疗的效果,为临床枪弹伤早期救治提供理论依据。方法:选取兰州地区健康成年长白约克品种猪8只,用95式步枪射击致双后肢贯通伤,距离25m。致伤后将两双后肢自体左右配对,分成VSD组和对照组。两组致伤6h行弹道清创消毒。分别在致伤后不同时间作细菌学计数,行病理学检查,5、72h行彩色多普勒超声检查。结果:治疗后细菌学计数两组比较差异有显著性(P0.05),病理学VSD组较对照组肉芽组织丰富,且炎细胞浸润、肌组织溶解变性及弹道表面菌落不明显。72h超声检查VSD组较对照组弹道及周边红蓝血流信号丰富,并见断裂肌束逐渐恢复。结论:VSD可降低枪弹软组织贯通伤细菌数量延缓感染时间、促进肉芽组织生长及局部血流量、减少创周组织水肿及降低血管通透性。
[Abstract]:Objective: to observe the effect of closed negative pressure drainage (VSD) on early treatment of gunshot soft tissue wound in pig limbs, and to provide theoretical basis for early treatment of gunshot wound. Methods: 8 healthy adult Landrace Yorkshire pigs in Lanzhou area were selected. The left and right hind limbs were matched with the left and right of the two hind limbs after the injury. The two groups were divided into two groups: the VSD group and the control group. The two groups were treated with ballistic debridement and disinfection at 6 hours after injury. The bacteriological count was made at different time after injury. Results: there was a significant difference in bacteriological count between the two groups after treatment, and the pathological VSD group had more granulation tissue and inflammatory cell infiltration than the control group. Muscle tissue dissolving and denaturation and the surface colony of ballistic surface were not obvious. 72 h ultrasound examination in VSD group was more abundant than that in control group in ballistics and peripheral red and blue blood flow signals. ConclusionVSD can reduce the number of bacteria in soft tissue penetrating wound, delay infection time, promote granulation tissue growth and local blood flow, reduce edema of wound tissue and reduce vascular permeability.
【作者单位】：兰州大学第二临床医学院;兰州军区兰州总医院骨科中心;
【基金】：全军“十一五”重点课题(编号:06G033)
【分类号】：R82

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