东南沿海某部皮肤真菌病流行病学调查及药敏试验

发布时间：2018-03-03 10:18

本文选题：皮肤真菌病　切入点：微生物敏感性试验　出处：《军医进修学院学报》2006年03期 　论文类型：期刊论文

【摘要】：目的:摸清该地区部队皮肤真菌病发病情况及菌种分布,筛选出高效、经济、实用的外用抗真菌药物。方法:对选定部队进行皮肤真菌病流行病学调查,采集标本,用改良KANE/FISCHER皮肤癣菌鉴定系统对采集的标本进行菌种分离和鉴定,并依据NCCLS2003年版M38-A方案对所分离菌种进行药敏试验。结果:该部队皮肤真菌病发病率为29.80%,其中足癣占75.31%,菌种主要为红色毛癣菌(73.30%)和须癣毛癣菌(21.21%)。所选8种药物对受试真菌均有较好的敏感性。结论:该部队皮肤真菌病发病率高,红色毛癣菌为主要致病菌,8种药物的MIC之间的差异有显著性,特比奈芬、布替奈芬为较适宜的药物。
[Abstract]:Objective: to find out the incidence and distribution of dermatomycosis in the army in this area, and to screen out effective, economical and practical antifungal drugs for external use. Methods: epidemiological investigation of dermatomycosis was carried out in selected troops, and specimens were collected. A modified KANE/FISCHER system for identification of dermatophytes was used to isolate and identify the collected specimens. The results showed that the incidence of dermatomycosis in the army was 29.80, including tinea pedis 75.31, mainly Trichophyton rubrum 73.30) and Trichophyton rubrum 21.210.Results: the incidence of dermatomycosis in the army was 29.80, including tinea pedis 75.31, Trichophyton rubrum 73.30) and Trichophyton rubrum 21.210.Results: the incidence of dermatomycosis in the army was 29.80. Conclusion: the incidence of dermatomycosis in this army is high. There was a significant difference in MIC between 8 kinds of drugs with Trichophyton rubrum as the main pathogenic bacteria. Terbinafine and butenafine were the most suitable drugs.
【作者单位】：解放军总医院皮肤科解放军总医院皮肤科解放军总医院皮肤科解放军总医院皮肤科北京大学第一医院皮肤科
【基金】：“十五”军队科研基金资助项目(01MA121)
【分类号】：R82

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