复方氨基酸胶囊对舰艇官兵免疫功能的影响

发布时间：2018-03-05 13:42

本文选题：军事人员　切入点：氨基酸类　出处：《解放军医学杂志》2012年01期 　论文类型：期刊论文

【摘要】：目的探讨复方氨基酸胶囊对舰艇官兵免疫功能的影响。方法将100名改良疲劳评定量表(MFIS)评分21分的舰艇官兵随机分为胶囊组和安慰剂组(n=50),分别给予复方氨基酸胶囊和安慰剂胶囊,在参加军事作业的情况下,连续服用14d。分别在服用的第1天和第14天采用免疫比浊法检测体液免疫指标IgG、IgM、IgA及补体C3、C4,采用流式细胞仪检测外周血T淋巴细胞亚群水平。结果服用第14天,胶囊组舰艇官兵IgG、IgGM及补体因子C3与第1天比较显著增高(P0.05),在对照组则无显著性差异;胶囊组舰艇官兵CD3+CD4+T淋巴细胞、CD3-CD19+B淋巴细胞与第1天比较均显著升高,CD3-CD56+NK淋巴细胞与第1天比较显著降低(P0.05),而对照组则无显著性差异。结论复方氨基酸胶囊能提高舰艇官兵的体液和细胞免疫功能。
[Abstract]:Objective to investigate the effect of compound amino acid capsule on the immune function of naval officers and soldiers. Methods 100 naval officers and soldiers with 21 marks of modified fatigue rating scale (MFIS) were randomly divided into capsule group and placebo group, and were given compound amino acid glue respectively. Capsules and placebo capsules, In the case of military operations, On the 1st and 14th day, the humoral immune index IgGMMA IgA and complement C3C4 were detected by immunoturbidimetry, and the levels of T lymphocyte subsets in peripheral blood were detected by flow cytometry. Results on the 14th day, the T lymphocyte subsets of peripheral blood were measured by flow cytometry. Compared with the 1st day, the IgGG G G GM and complement factor C 3 in the capsule group were significantly higher than those on the 1st day, but there was no significant difference in the control group. The CD3-CD19 B lymphocytes of CD3 CD4 T lymphocytes in the capsule group were significantly higher than those on the first day, and CD3-CD56 NK lymphocytes were significantly lower than those on the first day, but there was no significant difference in the control group. Conclusion the compound Amino Acid capsule is effective. Improve the humoral and cellular immune function of warship officers and soldiers.
【作者单位】：第二军医大学长海医院野战内科学研究所;解放军91257部队医院外科;
【基金】：全军“十一五”医药卫生科研基金重点课题(08Z022) 2010年深圳南山科技研发重点课题(2010-52)~~
【分类号】：R82

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