民航飞行人员的血清过氧化脂质水平

发布时间：2018-04-05 12:53

本文选题：飞行人员　切入点：过氧化脂质　出处：《中华放射医学与防护杂志》2003年04期

【摘要】：目的　观察职业性受高空宇宙射线照射的民航飞行人员血清过氧化脂质水平及抗氧化能力。方法　以化学比色法测定血清过氧化脂质、超氧化物歧化酶及总抗氧化活性 ;以宇宙辐射航线有效剂量计算软件CARI 6估算有效剂量。结果　飞行人员血清过氧化脂质、超氧化物歧化酶、总抗氧化活性均显著高于地面人员 (P 0 0 5 )。随着年均飞行小时、年均有效剂量的增加血清过氧化脂质水平有增加的趋势 ,但和累积飞行小时累积有效剂量及飞行人员的年龄没有平行关系。近期内飞行连续性变化 ,过氧化脂质水平也呈现相应的动态变化。结论　飞行人员体内脂质受到宇宙射线的氧化损伤 ,同时机体的抗氧化能力代偿性增强 ;近期飞行负荷、受照射频率明显影响血清过氧化脂质水平 ;过氧化脂质或可作为飞行人员辐射防护的监测指标。
[Abstract]:Objective to observe the level of serum lipid peroxidation and antioxidant capacity of civil aviation pilots exposed to high altitude cosmic rays.Methods Serum lipid peroxide, superoxide dismutase and total antioxidant activity were determined by chemical colorimetry, and the effective dose was estimated by CARI _ 6 software.Results Serum lipid peroxidation, superoxide dismutase and total antioxidant activity were significantly higher than those of ground workers (P 0.05).With the increase of average annual effective dose, the level of serum lipid peroxide increased, but there was no parallel relationship between the cumulative effective dose of flight hours and the age of pilots.In the near future, the changes of flight continuity and the level of lipid peroxide also showed a corresponding dynamic change.Conclusion oxidative damage of lipid in the body of pilots is caused by cosmic rays, and the compensatory ability of anti-oxidation is enhanced, and the level of lipid peroxide in serum is obviously affected by recent flight load and exposure frequency.Lipid peroxide may be used as a monitoring index for radiation protection of pilots.
【作者单位】：中国民航学院航空医学研究室中国民航学院航空医学研究室南开大学医学院
【基金】：民航总局科技基金资助项目 (99 3 3 )
【分类号】：R85

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