某部人群肾综合征出血热流行特征与基因分型研究

发布时间：2018-04-17 17:30

本文选题：肾综合征出血热 + 流行特征　；参考：《中国人兽共患病学报》2008年05期

【摘要】：目的了解某部人群肾综合征出血热(HFRS)流行特征及其感染型别,为本病防治工作提供科学依据。方法收集某部的疫情资料及相关信息资料,进行整理分析。同时采集HFRS疫区近期患者血清,应用RT-nested PCR结合SSCP对病人血清进行基因分型。结果某部1991-2006年报告病例403例,以散发为主,仅个别情况下长期密切接触疫源地才偶见局灶性暴发。报告病例呈现逐年下降趋势,2001年后呈零星散发;病例多集中在C、G、M等单位;以20～40岁发病居多;患者以战士为主,占72.21%;发病季节以春夏季高峰为主。基因分型结果证实当地近年来HFRS疫区从HTN向SEO转变,目前已经演变成以SEO为主的疫区。结论基本摸清某部近年HFRS流行特征,基因分型证实当地已经演变成以SEO为主的混合型疫区。
[Abstract]:Objective to investigate the epidemic characteristics and infection types of hemorrhagic fever with renal syndrome (HFRS) in a population in order to provide scientific basis for the prevention and treatment of HFRS.Methods data of epidemic situation and related information were collected and analyzed.At the same time, RT-nested PCR combined with SSCP were used to type the patients' serum in the recent period of HFRS epidemic area.Results 403 cases were reported in a department from 1991 to 2006, mainly sporadic cases. Only in a few cases did focal outbreaks occasionally occur in close contact with the foci for a long time.The reported cases showed a decreasing trend year by year and sporadic after 2001. Most of the cases occurred in the units such as Cladosporin M. Most of the cases occurred at the age of 2040. The patients were mainly soldiers (72.21) and the peak in spring and summer was the main disease season.The results of genotyping confirmed that the local HFRS epidemic area had changed from HTN to SEO in recent years, and now it has evolved into an epidemic area dominated by SEO.Conclusion the epidemic characteristics of HFRS in a certain area in recent years were basically investigated, and the genotyping confirmed that the region had evolved into a mixed epidemic area dominated by SEO.
【作者单位】：济南军区联勤部疾病预防控制中心济南军区联勤部疾病预防控制中心济南军区联勤部疾病预防控制中心济南军区联勤部疾病预防控制中心济南军区联勤部疾病预防控制中心济南军区联勤部疾病预防控制中心济南军区联勤部疾病预防控制中心济南军区联勤部疾病预防控制中心济南军区联勤部疾病预防控制中心济南军区联勤部疾病预防控制中心济南军区联勤部疾病预防控制中心济南军区联勤部疾病预防控制中心济南军区联勤部疾病预防控制中心济南军区联勤部卫生部济南军区联勤部卫生部山东武警总队医院
【分类号】：R82

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