某部潜艇艇员中胃幽门螺杆菌感染的血清流行病学调查

发布时间：2018-05-03 01:17

本文选题：胃幽门螺杆菌 + 血清CagA-HP-IgG　；参考：《解放军预防医学杂志》2002年02期

【摘要】：目的 :在潜艇艇员中进行胃幽门螺杆菌 (HoPylori,以下简称HP)感染的血清CagA -IgG流行病学调查 ,观察HP感染对潜艇艇员健康的影响 ,为卫生防治工作提供参考依据。方法 :对潜艇艇员 186人和普通人群 12 3人分别进行一般状况以及胃肠疾病诊治情况的问卷调查 ,并测定血清产细胞毒素幽门螺杆菌抗体 (CagA -HP -IgG)。结果 :潜艇人员中阳性检出率为 6 5 % ,普通人群阳性检出率为 5 1% ,两组比较 ,差异有统计学意义 (P 0 .0 5 )。潜艇艇员吸烟者CagA -HP -IgG阳性率为 73% ,不吸烟者CagA -HP -IgG阳性率为 5 9% ,两组无统计学意义。有胃肠症状者CagA -HP -IgG阳性率为 76 % ,无症状者CagA -HP -IgG阳性率为 5 5 % ,两者差异有显著性 (P 0 .0 1)。结论 :潜艇艇员中胃幽门螺杆菌感染率显著高于普通人群 ,且有胃肠症状者更为明显 ,为航海官兵胃病卫生防治工作提供了参考依据
[Abstract]:Objective: to investigate the epidemiology of Helicobacter pylori (HP) infection in the submarine crew, and to observe the effect of HP infection on the health of submarine crew. Methods: 186 submariners and 123 ordinary people were investigated with questionnaires on general status, diagnosis and treatment of gastrointestinal diseases, and serum antibodies against Helicobacter pylori were measured. Results: the positive rate of submarine personnel was 65%, and that of general population was 5.1%. The difference between the two groups was statistically significant (P 0.05). The positive rate of CagA HP IgG was 73% in submariners and 59% in nonsmokers. There was no significant difference between the two groups. The positive rate of CagA HP IgG was 76% in patients with gastrointestinal symptoms and 55% in asymptomatic patients with CagA HP IgG. There was a significant difference between the two groups (P 0. 01). Conclusion: the infection rate of Helicobacter pylori in the submarine crew is significantly higher than that in the general population, and it is more obvious in those with gastrointestinal symptoms, which provides a reference for the hygienic prevention and treatment of gastric diseases of marine officers and soldiers.
【作者单位】：海军后勤部卫生部海军后勤部卫生部海军总医院海军潜艇二支队卫生科海军青岛基地卫生处
【基金】：海军指令性课题 (No .98HW14)
【分类号】：R82

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