脑血氧饱和度的近红外光谱测量技术及其在超重条件下的应用

发布时间：2018-05-09 16:26

本文选题：血氧定量法 + 近红外光谱技术　；参考：《航天医学与医学工程》2003年05期

【摘要】：目的用近红外光谱技术对加速度作用后 (超重条件下 )的大鼠进行脑血氧饱和度 ( %SaO2 )的无损监测。方法制作头部不同程度缺血缺氧模型 ,抽血测量其血氧饱和度 ,并计算出与正常组之间的差值。同时测定出在 85 0nm和 760nm波长处缺血缺氧模型的光谱吸收强度 ,计算出与正常组之间的差值 ,并绘制出两者之间的关系曲线。根据关系曲线 ,通过用近红外光谱仪监测高 +Gz和推拉动作后的光谱吸收强度 ,计算出与 0Gz组差值 ,推测出加速度作用后脑血氧饱和度。结果由关系曲线推测出加速度作用后 ,大鼠脑血氧饱和度降低 ;推拉动作后 ,脑血氧饱和度降低更为明显。结论根据关系曲线 ,用近红外光谱技术可以无损监测脑血氧饱和度的变化
[Abstract]:Objective to monitor the cerebral oxygen saturation (SaO2) in rats after acceleration by near infrared spectroscopy (NIR). Methods the model of head ischemia and hypoxia was made and the blood oxygen saturation was measured and the difference between the blood oxygen saturation and the normal group was calculated. At the same time, the spectral absorption intensity of the model was measured at 85 0nm and 760nm wavelength, the difference between the model and the normal group was calculated, and the relationship curve between them was drawn. According to the relationship curve, the spectral absorption intensity of high Gz and push-pull action was monitored by near infrared spectrometer, and the difference with 0Gz group was calculated, and the cerebral oxygen saturation after acceleration was inferred. Results it was inferred from the relation curve that the cerebral oxygen saturation decreased after acceleration, and the decrease of cerebral oxygen saturation was more obvious after push-pull action. Conclusion according to the relation curve, the change of cerebral oxygen saturation can be monitored without damage by near infrared spectroscopy.
【作者单位】：中国科学院长春光学精密机械与物理研究所第四军医大学吉林军医学院第四军医大学吉林军医学院第四军医大学吉林军医学院
【基金】：20 0 1年全军医药卫生科研基金课题 “十五”面上项目 ( 0 1MA2 0 2 )
【分类号】：R85

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