高G对豚鼠前庭耳石器系统的影响

发布时间：2018-05-29 19:24

本文选题：高G + 耳石器　；参考：《第四军医大学学报》2002年19期

【摘要】：目的　研究高 G值对豚鼠前庭耳石器系统功能和形态学的影响 ,为航空航天活动中与此有关的问题提供实验依据 .方法　 38只豚鼠随机分为对照组 (n=10 )和高 G刺激组(n=2 8)两组 ,高 G组于给予 +10 Gy5 min的刺激后 0 .5 h断头处死取双侧椭圆囊行光镜、扫描和透射电镜观察 ,并应用核酸原位杂交技术对耳石器囊斑 HSP70 m RNA表达进行观察对比 .处死前观察各组豚鼠的行为学及前庭躯体和前庭眼动反射等行为学表现 .结果　 +10 Gy作用 5 min后 ,79%的豚鼠出现了耳石器受损的阳性行为学症状 .所有阳性症状均在 30 min内消失 .光镜下高 G刺激组有一定程
[Abstract]:Objective to study the effects of high G value on the function and morphology of vestibular otostoneal system in guinea pigs, and to provide experimental evidence for the related problems in aerospace activities. Methods Thirty eight guinea pigs were randomly divided into two groups: the control group (n = 10) and the high G stimulation group (n = 28). The rats in the high G group were killed at 0. 5 h after 10 Gy5 min of stimulation, and the bilateral elliptical sac were sacrificed for light microscope, scanning and transmission electron microscopy (TEM). The expression of HSP70 m RNA in otochthelial plaque was observed by in situ hybridization. Behavior and vestibular body and vestibular eye movement reflex were observed before death. Results positive behavioral symptoms were found in 79% of guinea pigs treated with 10 Gy for 5 min. All positive symptoms disappeared within 30 min. There is a certain course in high G stimulation group under light microscope.
【作者单位】：第四军医大学西京医院全军耳鼻咽喉专科中心第四军医大学西京医院全军耳鼻咽喉专科中心空军航空医学研究所空军航空医学研究所空军航空医学研究所空军航空医学研究所空军航空医学研究所
【分类号】：R85

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