某部装甲兵的精液质量分析

发布时间：2018-07-10 15:08

本文选题：装甲兵 + 噪声　；参考：《解放军预防医学杂志》2003年01期

【摘要】：目的 :探讨装甲兵训练噪声振动等物理因素是否对男性精液质量产生影响 ,为制定干预措施 ,降低和预防男性不育的发生提供依据。方法 :通过填写问卷调查表、体检及采用全自动精液分析系统分析精液质量、单细胞凝胶电泳和流式细胞仪检测DNA单双链损伤以及分析染色质结构等先进实验检测方法对某部装甲兵进行分子流行病学调查。结果 :暴露组精液中精子存活率 (6 2 .30± 2 5 .2 4 ) %和正常精子比率 (81.2 8± 11.18) %较对照组 (6 8.0 2± 2 5 .72 ) %和 (93.5 6± 5 .0 3) %下降 (P 0 .0 5 ,P 0 .0 1) ,精子畸形率则明显地增高〔(9.0 6± 11.15 ) %vs (7.37±10 .6 1) % ,P 0 .0 1〕 ,但均在正常值范围内 ,仅精子活力 (36 .4 % )明显低于正常值 (5 0 % )和对照组 (43.5 % ,P 0 .0 1)。彗星实验和染色质结构分析则无明显变化。结论 :长期受到噪声振动的影响 ,可能发生精液质量下降 ,但未发现精子DNA损伤增多。提示 ,加强装甲兵的个人防护 ,制定预防保健措施对提高男性生殖健康保健十分必要。
[Abstract]:Objective: to investigate whether physical factors such as noise and vibration in training of armored men have an effect on the quality of male semen, and to provide evidence for making intervention measures to reduce and prevent male infertility. Methods: the quality of semen was analyzed by filling out questionnaire, physical examination and automatic semen analysis system. Single cell gel electrophoresis (SGE) and flow cytometry (FCM) were used to detect DNA single and double strand damage and to analyze chromatin structure. Results: the sperm survival rate (62.30 卤25.24)% and the normal sperm rate (81.28 卤11.18)% in the exposed group were significantly lower than those in the control group (68.02 卤25.72)% and (93.56 卤5.03)% (P < 0.01). The sperm deformity rate was significantly increased (9.06 卤11.15) vs (7.37 卤10.61)% P 0.01, but only the sperm motility (36.4%) was significantly lower than the normal value (50%) and the control group (43.5% P 0.01). Comet assay and chromatin structure analysis showed no significant change. Conclusion: under the influence of noise vibration for a long time, semen quality may decline, but no DNA damage is found. It is suggested that it is necessary to strengthen personal protection and make preventive measures to improve male reproductive health care.
【作者单位】：解放军第二○二医院全军优生优育研究中心解放军第二○二医院全军优生优育研究中心解放军第二○二医院全军优生优育研究中心解放军第二○二医院全军优生优育研究中心解放军第二○二医院全军优生优育研究中心解放军第二○二医院全军优生优育研究中心解放军第二○二医院全军优生优育研究中心解放军第二○二医院全军优生优育研究中心
【基金】：全军医学科研“十五”基金重点课题 (No .0 1Z0 0 2 )
【分类号】：R82

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