铀在植入贫铀片和取片大鼠体内的动态变化和分布

发布时间：2018-10-09 07:15

【摘要】：目的　研究贫铀 (DU)弹片嵌入软组织后 ,铀在机体内的分布、动态变化 ,以及取片对铀浓度的影响。方法　将DU片植入大鼠肌肉 ,取片组在植入后第 5天取出DU片 ,在植入后第 1,3,7,15 ,2 0 ,2 6天收集样本 ,预处理 ,用激光荧光法测定铀含量。结果　植入DU大鼠所有样本铀浓度均显著高于正常对照组 ,尤其是肾脏、卵巢和胸骨铀浓度更高 ;单片组植片部位的肌肉铀浓度远高于未植片部位 ,其余组织铀浓度显著高于取片组。结论　植入DU片大鼠体内铀分布的主要器官是肾脏、卵巢和胸骨 ;取出嵌入的贫铀片可大大减少组织内的铀浓度 ,同时应剪去周围的肌肉组织。
[Abstract]:Aim to study the distribution and dynamic change of uranium in the body with depleted uranium (DU) shrapnel embedded in soft tissue, and the effect of uranium extraction on uranium concentration. Methods the DU films were implanted into the muscle of the rats. The DU films were taken out on the 5th day after implantation. The samples were collected on the 1st day after implantation. The samples were pretreated, and the content of uranium was determined by laser fluorescence method. Results uranium concentration in all samples of DU rats was significantly higher than that in normal control group, especially in kidney, ovary and sternum. The concentration of uranium in other tissues was significantly higher than that in the sample group. Conclusion the main organs of uranium distribution in DU rats are kidney, ovary and sternum, and the concentration of uranium in the tissue can be greatly reduced by removing the embedded depleted uranium film, and the surrounding muscle tissue should be cut off at the same time.
【作者单位】：第三军医大学复合伤研究所创伤烧伤复合伤国家重点实验室第三军医大学复合伤研究所创伤烧伤复合伤国家重点实验室北京放射医学研究所第三军医大学复合伤研究所创伤烧伤复合伤国家重点实验室第三军医大学复合伤研究所创伤烧伤复合伤国家重点实验室第三军医大学复合伤研究所创伤烧伤复合伤国家重点实验室北京放射医学研究所第三军医大学复合伤研究所创伤烧伤复合伤国家重点实验室第三军医大学复合伤研究所创伤烧伤复合伤国家重点实验室第三军医大学复合伤研究所创伤烧伤复合伤国家重点实验室
【基金】：全军“十五”指令性课题 ( 0 1L0 61)
【分类号】：R82

【参考文献】