脊髓爆震伤后前角运动神经元的形态学改变及早期救治研究
发布时间：2019-03-18 21:33
【摘要】：随着军事科技的发展和军队现代化建设的不断加强，各国军队的远程打击能力大大的得到提高，同其他常规武器相比，爆炸性武器具有更强的摧毁力和杀伤力，这就使得爆震伤在现代战争中所占的比重越来越大，爆震伤已经成为战争中脊柱、脊髓损伤的主要原因。由于脊髓爆震伤与机械性的ASCI在发生机制上有所不同，那么它们伤后的病理改变及救治方法也就不同，目前有关这方面的内容在国内外研究的都比较少，而现存的相关理论和治疗手段都已经落后，不能满足现代战争条件下脊髓爆震伤的要求，本课题的目的是研究脊柱、脊髓爆震伤后，脊髓前角运动神经元的病理生理变化并初步观察不同的治疗方法对其自然转归的影响，为临床有针对性的研究治疗方案具有一定的价值，，为提高我军战斗力，降低伤残率而服务。 一、爆震伤后脊髓前角运动神经元病理形态学变化 研究对象和材料：健康家兔30只，雌雄不拘，爆炸源采用军用单质金属炸药黑索金(RDX)，将其制作成0.9g铜壳圆柱状小型爆炸装置。
[Abstract]:With the development of military science and technology and the continuous strengthening of the modernization of the armed forces, the long-range strike capability of the armed forces of various countries has been greatly improved, and compared with other conventional weapons, explosive weapons have a stronger destructive power and killing power. This makes detonation injury more and more important in modern war. Detonation injury has become the main cause of spinal and spinal cord injury in war. Because the mechanism of spinal cord knock injury is different from that of mechanical ASCI, then their pathological changes and treatment methods are different. At present, there is little research on this aspect at home and abroad. And the existing relevant theories and treatment methods have been backward, can not meet the requirements of the modern war conditions of the spinal cord explosive injury, the purpose of this subject is to study the spinal cord, after the spinal cord explosion injury, the purpose of this topic is to study the spinal cord, spinal cord explosive injury, The pathophysiological changes of motor neurons in the anterior horn of spinal cord were observed and the effects of different treatment methods on their natural outcome were observed. It is of certain value for the clinical research and treatment of motor neurons in the anterior horn of the spinal cord and to improve the combat effectiveness of our army. Reduce the disability rate and serve. 1. Pathomorphological changes of motoneurons in anterior horn of spinal cord after blast injury: thirty healthy rabbits, both male and female, were used in this study. The explosive source was (RDX), a simple metal explosive for military use. The device was made into a 0.9 g copper shell cylindrical small explosive device.
【学位授予单位】：第四军医大学
【学位级别】：硕士
【学位授予年份】：2006
【分类号】：R82
本文编号：2443261
[Abstract]:With the development of military science and technology and the continuous strengthening of the modernization of the armed forces, the long-range strike capability of the armed forces of various countries has been greatly improved, and compared with other conventional weapons, explosive weapons have a stronger destructive power and killing power. This makes detonation injury more and more important in modern war. Detonation injury has become the main cause of spinal and spinal cord injury in war. Because the mechanism of spinal cord knock injury is different from that of mechanical ASCI, then their pathological changes and treatment methods are different. At present, there is little research on this aspect at home and abroad. And the existing relevant theories and treatment methods have been backward, can not meet the requirements of the modern war conditions of the spinal cord explosive injury, the purpose of this subject is to study the spinal cord, after the spinal cord explosion injury, the purpose of this topic is to study the spinal cord, spinal cord explosive injury, The pathophysiological changes of motor neurons in the anterior horn of spinal cord were observed and the effects of different treatment methods on their natural outcome were observed. It is of certain value for the clinical research and treatment of motor neurons in the anterior horn of the spinal cord and to improve the combat effectiveness of our army. Reduce the disability rate and serve. 1. Pathomorphological changes of motoneurons in anterior horn of spinal cord after blast injury: thirty healthy rabbits, both male and female, were used in this study. The explosive source was (RDX), a simple metal explosive for military use. The device was made into a 0.9 g copper shell cylindrical small explosive device.
【学位授予单位】：第四军医大学
【学位级别】：硕士
【学位授予年份】：2006
【分类号】：R82
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