模拟舰船冲击装置的研制及舰船眼部冲击伤的实验研究
发布时间：2019-07-06 16:09
【摘要】：舰船冲击伤作为水面舰船受水下非接触爆炸瞬间强烈冲击运动经船体和甲板传递作用于舰船上人员从而导致的不同程度的损伤,它甚至危及舰员生命,严重影响舰船战斗力。自80年代以来,国内外研究机构都对其给予了高度重视,进行了大量的研究,但这种舰船瞬间剧烈冲击运动对人员视觉系统产生何种效应即舰船眼部冲击伤的研究鲜有报道。视觉器官是人体最重要的感觉器官,视功能对战斗力的影响至关重要,舰船眼部冲击伤的研究对于保持和提高舰船人员战斗力具有重要意义,本研究旨在通过舰船冲击模拟装置进行动物实验研究分析舰船眼部冲击伤的伤情特点和致伤机制,为以后做救治研究制定防护措施奠定基础。 本研究首先在现有的舰船冲击伤动物模型基础上,创建出更接近实船效果,经济简便,易搬运携带的舰船冲击伤模拟装置;动物模型建立后,选择60g、80g、100g三个冲击加速度档次,分三组进行动物实验,每组随机5只青紫兰兔分别于伤前、伤后1h、1d、3d、7d、2w连续观察其眼部临床特点、测试其视觉电生理变化并进行眼底照相及荧光造影,然后第一组中另有6只分别在这六个时间点经颈动脉灌注硝酸镧,然后取眼球组织观察光电镜改变。第二组
文内图片：
图片说明：模拟舰船冲击装置设计草图
[Abstract]:Ship impact injury, as a kind of damage caused by the strong impact motion of the surface ship transmitted through the hull and deck, even endangers the life of the ship and seriously affects the combat effectiveness of the ship. Since 1980s, research institutions at home and abroad have attached great importance to it and carried out a lot of research, but there are few reports on the effect of instantaneous severe impact movement on the visual system of people, that is, the impact injury of the eye of the ship. Visual organ is the most important sensory organ of human body, and the influence of visual function on combat effectiveness is very important. The research of ship eye impact injury is of great significance to maintain and improve the combat effectiveness of ship personnel. The purpose of this study is to analyze the injury characteristics and injury mechanism of ship eye impact injury through animal experiment through ship impact simulation device, and to lay a foundation for future treatment and research to formulate protective measures. In this study, on the basis of the existing animal model of ship impact injury, a simulation device of ship impact injury is established, which is closer to the actual ship effect, economical and simple, and easy to carry. After the animal model was established, three shock acceleration grades of 60g, 80g and 100g were selected and divided into three groups. Five rabbits in each group were randomly divided into three groups. Five rabbits in each group were randomly divided into three groups before injury, 1 day, 3 days, 7 days, 2 weeks after injury, and their visual electrophysiological changes were measured and fundus photography and fluorescein angiography were performed. Then, 6 rabbits in the first group were perfused with lanthanum nitrate through carotid artery at these six time points. Then the eyeball tissue was taken to observe the changes of light electron microscope. Group II
【学位授予单位】：天津医科大学
【学位级别】：硕士
【学位授予年份】：2005
【分类号】：R82
本文编号：2511149
文内图片：
图片说明：模拟舰船冲击装置设计草图
[Abstract]:Ship impact injury, as a kind of damage caused by the strong impact motion of the surface ship transmitted through the hull and deck, even endangers the life of the ship and seriously affects the combat effectiveness of the ship. Since 1980s, research institutions at home and abroad have attached great importance to it and carried out a lot of research, but there are few reports on the effect of instantaneous severe impact movement on the visual system of people, that is, the impact injury of the eye of the ship. Visual organ is the most important sensory organ of human body, and the influence of visual function on combat effectiveness is very important. The research of ship eye impact injury is of great significance to maintain and improve the combat effectiveness of ship personnel. The purpose of this study is to analyze the injury characteristics and injury mechanism of ship eye impact injury through animal experiment through ship impact simulation device, and to lay a foundation for future treatment and research to formulate protective measures. In this study, on the basis of the existing animal model of ship impact injury, a simulation device of ship impact injury is established, which is closer to the actual ship effect, economical and simple, and easy to carry. After the animal model was established, three shock acceleration grades of 60g, 80g and 100g were selected and divided into three groups. Five rabbits in each group were randomly divided into three groups. Five rabbits in each group were randomly divided into three groups before injury, 1 day, 3 days, 7 days, 2 weeks after injury, and their visual electrophysiological changes were measured and fundus photography and fluorescein angiography were performed. Then, 6 rabbits in the first group were perfused with lanthanum nitrate through carotid artery at these six time points. Then the eyeball tissue was taken to observe the changes of light electron microscope. Group II
【学位授予单位】：天津医科大学
【学位级别】：硕士
【学位授予年份】：2005
【分类号】：R82
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