中西医结合治疗顽固性鼻出血30例临床观察

发布时间：2017-12-30 20:01

本文关键词：中西医结合治疗顽固性鼻出血30例临床观察　出处：《中医杂志》2014年17期 　论文类型：期刊论文

【摘要】：目的观察中西医结合治疗顽固性鼻出血的临床疗效。方法 90例顽固性鼻出血患者随机分为鼻内镜组、阿莫西林组、一清胶囊组,每组30例。鼻内镜组使用鼻内镜微波治疗;阿莫西林组在鼻内镜微波治疗后服用阿莫西林胶囊,每次0.5g,每天3次,连服3~5天;一清胶囊组在阿莫西林组治疗基础上再服用一清胶囊,每次1g,每日3次,连服2周。对患者治疗前后尿激酶型纤溶酶原激活物(uPA)及其受体(uPAR)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)及血浆纤维蛋白原水平(FIB)进行检测。同时观察临床疗效、治愈次数。结果一清胶囊组临床疗效总有效率90.0%,显著高于鼻内镜组的63.3%(P0.05),与阿莫西林组的80.0%比较,差异无统计学意义(P0.05)。一清胶囊组一次治愈率显著高于鼻内镜组与阿莫西林组(P0.05)。治疗前后鼻内镜组uPA、PT、FIB,阿莫西林组uPA、PT、APTT、FIB,一清胶囊组uPA、uPAR、PT、APTT、TT及FIB比较差异均有统计学意义(P0.05);治疗后一清胶囊组uPA、uPAR、APTT、TT、FIB与鼻内镜组及阿莫西林组,PT与鼻内镜组比较差异均有统计学意义(P0.05)。结论中西医结合治疗顽固性鼻出血可提高临床疗效,改善凝血指标。
[Abstract]:Objective to observe the clinical effect of combined traditional Chinese and western medicine on intractable epistaxis. Methods 90 patients with intractable epistaxis were randomly divided into three groups: nasal endoscope group, amoxicillin group and Yiqing capsule group. There were 30 cases in each group. Amoxicillin group was treated with amoxicillin capsule (0.5 g, 3 times a day, 3 days) after endoscopic microwave therapy. The Yiqing capsule group was treated with Yiqing capsule on the basis of amoxicillin treatment, 1 g each time, 3 times a day. Before and after treatment, urokinase type plasminogen activator (UPA) and its receptor, prothrombin time (PTT), activated partial thromboplasminogen activator (APTT). Thrombin time (TTT) and plasma fibrinogen level were measured. The clinical efficacy and cure times were observed. Results the total effective rate of Yiqing capsule group was 90.0%. It was significantly higher than that in nasal endoscopy group (63.3%) and amoxicillin group (80.0%%). The cure rate of Yiqing capsule group was significantly higher than that of nasal endoscopy group and amoxicillin group (P 0.05). In amoxicillin group, there were significant differences in APTTT TT and FIB between Amoxicillin group and Yiqing capsule group (P 0.05). After treatment, the patients in the Yiqing capsule group were treated with TTFIB, UPA-UPA-UPARP-APTTTI-TTFIB, nasal endoscopy group and amoxicillin group. Conclusion the treatment of intractable epistaxis with combination of traditional Chinese medicine and western medicine can improve the clinical efficacy and blood coagulation index.
【作者单位】：延边大学附属医院;
【分类号】：R765.23
【正文快照】： 顽固性鼻出血是指鼻腔内反复性出血,好发于鼻腔中后部。此处扩张血管多易形成血管丛,而且容易引起出血,出血时量大,来势凶猛,重者可导致失血性休克进而危及生命,是耳鼻咽喉科急、重症之一[1]。较为传统的止血方法有局部压迫、血管结扎,以及前后鼻孔填塞、栓塞或者使用血管收缩

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