缺血性中风急性期中西医结合治疗临床研究

发布时间：2018-01-09 09:37

本文关键词：缺血性中风急性期中西医结合治疗临床研究　出处：《山东中医药大学》2011年硕士论文　论文类型：学位论文

【摘要】：目的:对缺血性中风急性期中西医结合综合治疗方案在临床中的应用进行随机对照临床试验,观察并评价其临床疗效。方法:将所有入选病例随机分为两组,分别为中西医结合综合治疗试验组和西医综合治疗对照组,对两组病例治疗情况进行观测和记录,用统计学方法处理相关数据,进行疗效评价和科学总结。结果:治疗后两组的临床症状及体征均得到了改善,但两组的改善特点存在差异。两组疗效、神经功能缺损(NIHSS)评分、中医病类诊断标准评分、中医证候量化积分、总的生活能力状态(ADL)评分及生存质量(QLI)指数评分比较在治疗后7、14、28天后的改变存在明显差异。两组患者治疗后NIHSS评分均有明显改善,在治疗后14天时试验组优于对照组(P0.05),28天时明显优于对照组(P0.01)。治疗后28天时中医病类诊断标准评分、中医证候量化积分、ADL评分比较,试验组明显优于对照组(P0.01)。试验组在改善病人的生存质量(QLI)指数方面明显优于对照组(P0.01)。治疗后28天时试验组基本恢复病例占31.43%,显著进步者占65.71%,进步者占2.86%,对照组基本恢复者占7.35%,显著进步者占22.06%,进步者占66.18%,稍进步者占4.41%,试验组临床总疗效优于对照组(P0.05)。两组TC、TG、LDL-C、Fg均有降低,试验组优势更加明显(P0.01)。治疗后对照组ALT明显升高(P0.01),WBC明显降低(P0.05)。结论: 1.中西医结合综合治疗方案合理应用能够降低缺血性中风急性期患者死亡率,明显促进患者的神经功能恢复,改善患者的日常生活能力,提高患者远期生存质量,降低致残率。2.能够较好地控制血脂异常,降低纤维蛋白原,改善凝血功能。
[Abstract]:Objective : To observe and evaluate the clinical curative effect of integrated traditional Chinese medicine and western medicine in the treatment of ischemic stroke . Methods : All selected cases were randomly divided into two groups , the combination of western medicine and western medicine combination therapy group and western medicine comprehensive treatment control group , the treatment of two groups were observed and recorded , the correlation data was treated by statistical method , and the curative effect evaluation and scientific summary were carried out . Results : Compared with the control group ( P0.01 ) , the clinical symptoms and signs of the two groups were significantly better than those in the control group ( P0.01 ) . Conclusion : 1 . Reasonable application of integrated traditional Chinese medicine and western medicine can reduce the mortality of patients in acute stage of ischemic stroke , obviously promote the recovery of nerve function of patients , improve the daily life ability of the patients , improve the long - term survival quality of the patients and reduce the disability rate .

【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2011
【分类号】：R743.3

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