中西医结合治疗对老年2型糖尿病患者微血管病变的影响

发布时间：2018-01-27 16:23

本文关键词： 中西医结合型糖尿病糖尿病微血管病变　出处：《中国老年学杂志》2014年08期 　论文类型：期刊论文

【摘要】：目的观察中西医结合治疗老年2型糖尿病患者微血管病变的影响。方法老年2型糖尿病(T2DM)患者100例,随机分为对照组和治疗组,每组50例,对照组采用常规西药治疗方法;治疗组在对照组基础上同时加用自拟中药方治疗,两组疗程均为2个月。观察两组治疗前后患者临床疗效、神经传导速度(NCV)、神经病变积分(MDNS)、全血黏度、血浆黏度、血细胞容积、空腹血糖(FPG)、餐后2 h血糖(2 h PG)、24 h尿蛋白及血脂水平变化。结果治疗组总有效率88.0%明显高于对照组总有效率78%(χ2=4.201,P0.05);两组治疗后NCV、MDNS的水平与治疗前比较差异(P0.05);治疗组患者治疗后NCV、MDNS的水平与对照组治疗后比较差异(P0.05);两组治疗后全血黏度、血浆黏度、血细胞容积的变化与治疗前比较差异(P0.05);治疗组患者治疗后全血黏度、血浆黏度的水平与对照组治疗后比较差异(P0.05);两组治疗后FPG、2 h PG、HbA1c、甘油三酯(TG)、总胆固醇(TC)的变化与治疗前比较差异(P0.05);治疗组患者治疗后FPG、2 h PG、HbA1c、TG、TC的变化与对照组治疗后比较差异均无统计学意义(P0.05)。结论中西医结合治疗老年T2DM患者及改善糖尿病微血管病变疗效显著。
[Abstract]:Objective to observe the effect of integrated traditional Chinese and western medicine on microvascular lesions in elderly patients with type 2 diabetes mellitus. Methods 100 elderly patients with type 2 diabetes mellitus (T2DM) were randomly divided into control group (n = 50) and treatment group (n = 50). The control group was treated with routine western medicine. Treatment group on the basis of the control group at the same time with self-made traditional Chinese medicine treatment, the two groups were treated for 2 months. Observe the two groups before and after treatment of patients with clinical efficacy, nerve conduction velocity (NCVV). Neuropathy score MDNSG, whole blood viscosity, plasma viscosity, blood cell volume, fasting blood glucose and FPGG, 2 h postprandial blood glucose and 2 h PG2). Results the total effective rate of treatment group (88.0%) was significantly higher than that of control group (78%) (蠂 ~ 2 = 4.201, P 0.05). After treatment, the level of NCVN MDNS in the two groups was significantly different from that before treatment (P 0.05). The level of NCVN MDNS in the treatment group was significantly higher than that in the control group (P 0.05). The changes of whole blood viscosity, plasma viscosity and blood cell volume after treatment in the two groups were significantly different from those before treatment (P 0.05). After treatment, the whole blood viscosity and plasma viscosity in the treatment group were significantly different from those in the control group (P 0.05). The changes of PGN HbA1c, triglyceride TGN and total cholesterol TCC in two groups after treatment were significantly different from those before treatment (P 0.05). The patients in the treatment group were treated with PGN HbA1cTG for 2 h after treatment. There was no significant difference in TC between the control group and the control group (P 0.05). Conclusion the therapeutic effect of integrated traditional Chinese and western medicine on the elderly patients with T2DM and the improvement of diabetic microangiopathy is significant.
【作者单位】：成都市第一人民医院;成都中医药大学;
【分类号】：R587.2
【正文快照】： 糖尿病是老年人常见病和多发病,随着病程延长患者会出现各种各样并发症,尤以微血管病变多见。在糖尿病的早期,病情控制不好时,可出现微血管改变,加速动脉粥样硬化〔1~3〕。可使糖尿病的微血管病变和肾脏并发症进一步加重,如脑卒中、心力衰竭,主动脉病变和高血压视网膜病变加重

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