中西医结合治疗对尘螨过敏的咳嗽变异型哮喘患者肺功能及1年复发率的影响

发布时间：2018-02-01 18:26

本文关键词： 咳嗽变异型哮喘尘螨中西医结合疗法肺功能年复发率　出处：《新中医》2011年08期 　论文类型：期刊论文

【摘要】：目的:观察必可酮(丙酸倍氯米松气雾剂)、宁肺丸、阿罗格治疗尘螨过敏的咳嗽变异型哮喘(CVA)患者肺功能的改善情况和1年复发率。方法:将138例CVA患者随机分为3组,每组46例。治疗组A:予必可酮、宁肺丸、阿罗格治疗;治疗组B:予必可酮、宁肺丸治疗;对照组:予必可酮治疗。疗程12周,观察治疗前及治疗12周时的第1秒用力呼气容量(FEV)1、用力肺活量(FVC)、呼气峰流速(PEF),以及治疗满1年时每组复发率。结果:纳入统计,治疗组A 43例,治疗组B44例,对照组43例,各组FVC、FEV1、PEF指标治疗前后比较,差异均有显著性意义(P0.05)。FVC治疗前后差值组间比较,治疗组A较其它2组均有明显变化(P0.05)。FEV1、PEF治疗前后差值组间比较,差异无显著性意义(P0.05)。1年复发率治疗组A 46.5%、治疗组B 63.6%、对照组74.4%。3组复发率比较,差异有显著性意义(P0.05,)。结论:必可酮、宁肺丸、阿罗格对尘螨过敏的CVA患者可明显改善其FVC,降低1年复发率,并且有可能改善CVA患者的小气道通气功能障碍。
[Abstract]:Objective: to observe Bicolone (beclomethasone propionate aerosol) and Ningfei pills. Improvement of pulmonary function and 1 year recurrence rate in patients with cough variant asthma with dust mite allergy. Methods: 138 patients with CVA were randomly divided into 3 groups. There were 46 cases in each group. Group A was treated with bitoxone, Ningfei pills and arogel. Group B: treated with Bikodone and Ningfei pills; The control group was treated with buconone for 12 weeks. The forced expiratory volume (FEV1), forced vital capacity (FV) and peak expiratory flow rate (PEF) were observed at 1 seconds before treatment and 12 weeks after treatment. Results: 43 cases in treatment group, 44 cases in treatment group and 43 cases in control group. There was significant difference between the two groups before and after treatment, and the difference between the treatment group A and the other two groups were significant. There was no significant difference between the two groups before and after PEF treatment. The recurrence rate of one year was 46.5 in treatment group and B 63.6% in treatment group. The recurrence rate of the control group 74.4.3 was significantly higher than that of the control group (P 0.05). Conclusion: the patients with CVA who are allergic to dust mite can obviously improve their FVC. Reduce 1-year recurrence rate and may improve small airway ventilation dysfunction in CVA patients.
【作者单位】：成都市第一人民医院;
【基金】：四川省中医药管理局课题(编号:200605)
【分类号】：R562.25
【正文快照】： 咳嗽变异型哮喘(cough variant asthma,CVA)是以咳嗽为主要临床表现的一种特殊类型的哮喘,其发病机理与典型哮喘的发病机理相似[1],CVA成人患者中有30%～40%可发展为典型哮喘,故认为CVA是典型哮喘的前驱状态[2]。本研究以具有确切疗效的必可酮(丙酸倍氯米松气雾剂)作为对照,

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