中西医结合治疗肾上腺肿瘤术后皮质功能减退的临床疗效

发布时间：2018-02-25 19:37

本文关键词： 中西医结合治疗肾上腺肿瘤术肾上腺皮质功能减退临床疗效　出处：《中华中医药学刊》2016年06期 　论文类型：期刊论文

【摘要】：目的:探讨分析中西医结合方法对肾上腺肿瘤术后引起的肾上腺皮质功能减退进行治疗的临床疗效。方法:选择2014年5月—2015年8月期间医院收治的肾上腺肿瘤术后皮质功能不足患者共68例,将其采用随机数字表的方法分为对照组和观察组,每组各34例。对照组患者给予西医进行治疗,观察组患者在对照组治疗的基础上给予中西医结合进行治疗,对比两组患者的临床疗效及不良反应情况。结果:观察组患者总有效率达97.06%,不良反应发生率为8.82%;对照组患者总有效率为73.53%,不良反应发生率为29.41%,差异具有统计意义(P0.05)。经治疗后,观察组患者晨8 h血浆皮质醇、晨8 h血浆促肾上腺皮质激素(ACTH)、24 h尿游离皮质醇(UFC)、17-羟皮质类固醇(17-OHCS)及17-酮类固醇(17-KS)含量值显著高于对照组(P0.05)。结论:中西医结合治疗肾上腺肿瘤术后皮质功能不足,起效迅速、安全,且不良反应轻微,可应用于医学领域,也对于气阴两虚型糖尿病肾病等患者具有临床意义,值得临床推广应用。
[Abstract]:Objective: to investigate the clinical effect of combined traditional Chinese and western medicine in the treatment of adrenal cortical dysfunction caused by adrenal neoplasms. Methods: from May 2014 to August 2015, adrenal neoplasms were treated in hospital. There were 68 cases of posterior cortical insufficiency. The patients in the control group were treated with western medicine, and the patients in the observation group were treated with the combination of traditional Chinese and western medicine on the basis of the treatment in the control group. Results: the total effective rate of the patients in the observation group was 97.06 and the incidence rate of the adverse reactions was 8.82. The total effective rate of the patients in the control group was 73.53 and the incidence of the adverse reactions was 29.41. The difference was statistically significant after treatment. The patients in the observation group were treated with cortisol at 8 hours in the morning. The levels of plasma ACTH in 24 h urine free corticosteroid 17 OHCS and 17 KS were significantly higher than those in the control group (P 0 05). Conclusion: the cortical function of adrenal neoplasms treated with integrated traditional Chinese and western medicine is insufficient and the effect is rapid. Safety and mild adverse reactions can be used in the field of medicine, but also for patients with deficiency of both qi and yin diabetic nephropathy and other patients with clinical significance, worthy of clinical application.
【作者单位】：宁波市医疗中心李惠利医院泌尿外科;上海市中西医结合医院肾内科;
【基金】：上海市青浦区科学技术发展基金项目[2014-16(12-E-21)]
【分类号】：R736.6

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