中西医结合治疗消化性溃疡合并出血及对胃内pH的影响

发布时间：2018-04-07 15:14

本文选题：消化性溃疡　切入点：上消化道出血　出处：《中华中医药学刊》2016年08期

【摘要】：目的:探究中西医结合治疗消化性溃疡合并上消化道出血的疗效及对胃内pH的影响。方法:选取90例消化性溃疡合并上消化道出血的患者作为研究对象,并将其按数字随机分组法分为对照组和观察组,每组45例。给予对照组泮托拉唑联合血凝酶进行治疗,观察组则在此基础上结合中医辨证分型方法联合治疗,比较两组患者的止血时间以及治疗效果,监测比较两组患者胃内pH的变化。结果:观察组的止血时间为(32.18±5.9)h,总有效率为91.11%;对照组的相应值分别为(50.24±8.17)h,71.11%。观察组的止血时间明显短于对照组,总有效率也高于对照组,且差异具有统计学意义(P0.05);两组患者24 h胃内平均pH、到达胃内pH6.0的时间及胃内pH6.0的维持时间无显著性差异(P0.05)。结论:中西医结合方法治疗消化性溃疡合并出血可有效缩短患者的止血时间,治疗效果显著,值得临床推广应用。
[Abstract]:Objective: to explore the effect of integrated traditional Chinese and western medicine on peptic ulcer with upper gastrointestinal bleeding and its effect on gastric pH.Methods: 90 patients with peptic ulcer complicated with upper gastrointestinal bleeding were selected and divided into control group (n = 45) and observation group (n = 45).The control group was treated with pam Tora zole combined with hemagglutinin, while the observation group was treated with TCM syndrome differentiation method. The hemostasis time and therapeutic effect of the two groups were compared, and the changes of gastric pH were monitored and compared between the two groups.Results: the hemostatic time of the observation group was 32.18 卤5.9 hours, the total effective rate was 91.11, and the corresponding values of the control group were 50.24 卤8.17 hours and 71.11, respectively.The hemostasis time in the observation group was significantly shorter than that in the control group, and the total effective rate was also higher than that in the control group, and the difference was statistically significant (P 0.05), and there was no significant difference between the two groups in the mean intragastric pH, the time to reach the intragastric pH6.0 and the maintenance time of the intragastric pH6.0 in the two groups.Conclusion: the treatment of peptic ulcer complicated with hemorrhage by integrated traditional Chinese and western medicine can effectively shorten the hemostasis time of the patients, and the therapeutic effect is remarkable, and it is worth popularizing in clinic.
【作者单位】：泸州医学院附属医院消化内科;
【基金】：国家自然科学基金项目(81201950)
【分类号】：R573.1

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